5%CE%B1 reductase_II/SRD5A2, 5%CE%B1 reductase_inhibitor/5α-Reductase inhibitor

5% CE% B1 reductase_II / SRD5A2: 3-oxo-5α-steroid 4-dehydrogenase 2 ni enzyme ko mubantu igizwe na gen SRD5A2 . Nimwe muri isozymes eshatu za 5α-reductase.
5% CE% B1 reductase_inhibitor / 5α-Kugabanya inhibitor: 5α-Kugabanya inhibitori ( 5-ARIs ), izwi kandi nka dihydrotestosterone ( DHT ) ikumira , ni urwego rwimiti ifite ingaruka za antandrogeneque zikoreshwa cyane cyane mukuvura prostate nini no guta umusatsi. Rimwe na rimwe zikoreshwa mu kuvura imikurire ikabije ku bagore kandi nkigice cyo kuvura imisemburo ku bagore bahindura ibitsina.
5% CE% B1 reductase_ubwoko_1 / SRD5A1: 3-oxo-5α-steroid 4-dehydrogenase 1 ni enzyme ko mubantu igizwe na gen SRD5A1 . Nuburyo bumwe muburyo butatu bwa steroid 5α-reductase.
5% CE% B1 reductase_ubwoko_2 / SRD5A2: 3-oxo-5α-steroid 4-dehydrogenase 2 ni enzyme ko mubantu igizwe na gen SRD5A2 . Nimwe muri isozymes eshatu za 5α-reductase.
5% CE% B1 reductase_ubwoko_I / SRD5A1: 3-oxo-5α-steroid 4-dehydrogenase 1 ni enzyme ko mubantu igizwe na gen SRD5A1 . Nuburyo bumwe muburyo butatu bwa steroid 5α-reductase.
5% CE% B1 reductase_ubwoko_II / SRD5A2: 3-oxo-5α-steroid 4-dehydrogenase 2 ni enzyme ko mubantu igizwe na gen SRD5A2 . Nimwe muri isozymes eshatu za 5α-reductase.
5% CE% B2-Androstane / Etiocholane: Etiocholane , izwi kandi nka 5β-androstane cyangwa 5-epiandrostane , ni androstane (C19) steroid. Ni 5β-isomer ya androstane. Etiocholanes irimo 5β-androstanedione, 5β-dihydrotestosterone, 3α, 5β-androstanediol, 3β, 5β-androstanediol, etiocholanolone, epietiocholanolone, na 3α, 5β-androstanol.
5% CE% B2-Androstane-3,17-dione / Etiocholanedione: Etiocholanedione , izwi kandi nka 5β-androstanedione cyangwa nka etiocholane-3,17-dione , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya andorogene nka testosterone, dihydrotestosterone, dehydroepiandrosterone (DHEA), na Drosta. Ni C5 epimer ya androstanedione (5α-androstanedione). Nubwo idafite ibikorwa bya androgeneque nkibindi 5β byagabanijwe na steroid, etiocholanedione ifite ibikorwa byibinyabuzima byonyine. Urusange rwasanze rufite ingaruka zikomeye za haematopoietic muburyo butandukanye. Byongeye kandi, byagaragaye ko biteza imbere kugabanya ibiro ku nyamaswa ndetse no mu bushakashatsi bw'ubuvuzi bw'impumyi ebyiri, bugenzurwa na platbo mu bantu bwakozwe mu 1993. Izi ngaruka ngo zisa n'iza DHEA. Bitandukanye na DHEA ariko, etiocholanedione ntishobora guhindurwa cyane mumisemburo ya steroid nka andorogene na estrogene.
5% CE% B2-Androstane-3% CE% B1,17% CE% B2-diol / 3α-Etiocholanediol: 3α-Etiocholanediol , cyangwa etiocholanediol gusa, izwi kandi nka 3α, 5β-androstanediol cyangwa nka etiocholane-3α, 17β-diol , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya testosterone. Yakozwe kuva 5β-dihydrotestosterone kandi ihinduka na etiocholanolone.
5% CE% B2-Androstane-3% CE% B2,17% CE% B2-diol / 3β-Etiocholanediol: 3β-Etiocholanediol , cyangwa epietiocholanediol , izwi kandi nka 3β, 5β-androstanediol cyangwa nka etiocholane-3β, 17β-diol , ni etiocholane (5β-androstane) steroid na metabolite ya endogenous ya testosterone. Yakozwe kuva 5β-dihydrotestosterone kandi ihinduka epietiocholanolone.
5% CE% B2-Androstanediol / Etiocholanediol: Etiocholanediol (5β-androstanediol) irashobora kwerekeza kuri: 3α-Etiocholanediol - interogenous intermedia hagati ya epiandrosterone 3β-Etiocholanediol - interogenous intermedia hagati ya epietiocholanolone
5% CE% B2-Androstanedione / Etiocholanedione: Etiocholanedione , izwi kandi nka 5β-androstanedione cyangwa nka etiocholane-3,17-dione , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya andorogene nka testosterone, dihydrotestosterone, dehydroepiandrosterone (DHEA), na Drosta. Ni C5 epimer ya androstanedione (5α-androstanedione). Nubwo idafite ibikorwa bya androgeneque nkibindi 5β byagabanijwe na steroid, etiocholanedione ifite ibikorwa byibinyabuzima byonyine. Urusange rwasanze rufite ingaruka zikomeye za haematopoietic muburyo butandukanye. Byongeye kandi, byagaragaye ko biteza imbere kugabanya ibiro ku nyamaswa ndetse no mu bushakashatsi bw'ubuvuzi bw'impumyi ebyiri, bugenzurwa na platbo mu bantu bwakozwe mu 1993. Izi ngaruka ngo zisa n'iza DHEA. Bitandukanye na DHEA ariko, etiocholanedione ntishobora guhindurwa cyane mumisemburo ya steroid nka andorogene na estrogene.
5% CE% B2-Androsterone / Etiocholanolone: Etiocholanolone , izwi kandi nka 5β-androsterone , kimwe na 3α-hydroxy-5β-androstan-17-imwe cyangwa etiocholan-3α-ol-17-imwe , ni etiocholane (5β-androstane) steroid kimwe na endogenous 17- ketosteroide ikomoka kuri metabolism ya testosterone. Itera umuriro, immunostimulation, na leukocytose, kandi ikoreshwa mugusuzuma imikorere ya cortex ya adrenal, imikorere yamagufwa, no muburwayi bwa neoplastique kugirango ikangure sisitemu yumubiri. Etiocholanolone izwi kandi ko ari inzitizi ya androstane neurosteroid, ikora nka moderi nziza ya allosteric modulator ya reseptor ya GABA A , kandi ikagira ingaruka za anticonvulsant. Enantiomer idasanzwe ya etiocholanolone irakomeye cyane nka moderi nziza ya allosteric modulator ya GABA A yakira kandi nka anticonvulsant kuruta imiterere karemano.
5% CE% B2-Cholestane / Coprostane: Coprostane , izwi kandi nka 5β-cholestane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid, nka ecdysone na coprostanol.
5% CE% B2-DHT / 5β-Dihydrotestosterone: 5β-Dihydrotestosterone ( 5β-DHT ), izwi kandi nka 5β-androstan-17β-ol-3-imwe cyangwa nka etiocholan-17β-ol-3-imwe , ni etiocholane (5β-androstane) steroid kimwe na metabolite idakora ya testosterone yakozwe na 5β-reductase mu mwijima no mu magufa no hagati mu mikorere ya 3α, 5β-androstanediol na 3β, 5β-androstanediol kandi, muri bo, etiocholanolone na epietiocholanolone. Bitandukanye na isomer yayo 5α-dihydrotestosterone, 5β-DHT ntishobora guhuza cyangwa guhuza intege nke cyane na reseptor ya androgene. 5β-DHT irazwi cyane muri metabolite ya testosterone muri ibyo, kubera guhuza impeta ya A na B mu cyerekezo cya cis , ifite imiterere ya molekulari cyane, kandi ibyo bishobora kuba bifitanye isano no kubura ibikorwa bya andorogene. 5β-DHT, bitandukanye na 5α-DHT, nayo idakora mubijyanye nibikorwa bya neurosteroid, nubwo metabolite yayo, etiocholanolone, ifite ibikorwa nkibi.
5% CE% B2-Dihydroprogesterone / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-Dihydrotestosterone / 5β-Dihydrotestosterone: 5β-Dihydrotestosterone ( 5β-DHT ), izwi kandi nka 5β-androstan-17β-ol-3-imwe cyangwa nka etiocholan-17β-ol-3-imwe , ni etiocholane (5β-androstane) steroid kimwe na metabolite idakora ya testosterone yakozwe na 5β-reductase mu mwijima no mu magufa no hagati mu mikorere ya 3α, 5β-androstanediol na 3β, 5β-androstanediol kandi, muri bo, etiocholanolone na epietiocholanolone. Bitandukanye na isomer yayo 5α-dihydrotestosterone, 5β-DHT ntishobora guhuza cyangwa guhuza intege nke cyane na reseptor ya androgene. 5β-DHT irazwi cyane muri metabolite ya testosterone muri ibyo, kubera guhuza impeta ya A na B mu cyerekezo cya cis , ifite imiterere ya molekulari cyane, kandi ibyo bishobora kuba bifitanye isano no kubura ibikorwa bya andorogene. 5β-DHT, bitandukanye na 5α-DHT, nayo idakora mubijyanye nibikorwa bya neurosteroid, nubwo metabolite yayo, etiocholanolone, ifite ibikorwa nkibi.
5% CE% B2-Estran-3% CE% B1-ol-17-umwe / 19-Noretiocholanolone: 19-Noretiocholanolone , izwi kandi nka 5β-estran-3α-ol-17-imwe , ni metabolite ya nandrolone (19-nortestosterone) na bolandione (19-norandrostenedione) ikorwa na 5α-reductase. Ari kurutonde rwibintu bibujijwe n'ikigo cy'isi gishinzwe kurwanya ibiyobyabwenge kuko ari metabolite igaragara ya nandrolone, anabolike-androgeneque steroid (AAS).
5% CE% B2-Ethyl-etiocholane / 5β-Inda: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-Ethyletiocholane / 5β-Gutwita: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-Gutwita-3,20-dione / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-Inda / 5β-Inda: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-Gutwita-3,20-dione / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-Inda-3% CE% B1,20% CE% B1-diol 3-glucuronide / glucuronide ya Pregnanediol: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-Gutwita-3% CE% B1,20% CE% B1-diol 3% CE% B1-glucuronide / glucuronide ya Pregnanediol: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-Gutwita-3% CE% B1,20% CE% B1-diol glucuronide / Pregnanediol glucuronide: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-Gutwita / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-Kugabanya / 5β-Kugabanya: 5β-Kugabanya , cyangwa Δ 4 -3-oxosteroid 5β-reductase (EC 1.3.1.3 , 3-oxo-Δ 4 -steroid 5β-reductase , androstenedione 5β-reductase , cholestenone 5β-reductase , cortisone 5β-reductase , cortisone Δ 4 -5β-reductase , steroid 5β-reductase , testosterone 5β-reductase , Δ 4 -3-ketosteroid 5β-reductase , Δ 4 -5β-reductase , Δ 4 -hydrogenase , 4,5β-dihydrocortisone: NADP + Δ 4 -oxidoreductase , 3-oxo-5β-steroid: NADP + Δ 4 -oxidoreductase ) ni enzyme ifite izina ritunganijwe 5β-cholestan-3-imwe: NADP + 4,5-oxydeductase . Iyi misemburo itera imiti ikurikira (1) 5β-cholestan-3-imwe + NADP + cholest-4-en-3-imwe + NADPH + H + (2) 17,21-dihydroxy-5β-inda-3,11,20-trione + NADP + cortisone + NADPH + H +
5% CE% B2-Kugabanya / 5β-Kugabanya: 5β-Kugabanya , cyangwa Δ 4 -3-oxosteroid 5β-reductase (EC 1.3.1.3 , 3-oxo-Δ 4 -steroid 5β-reductase , androstenedione 5β-reductase , cholestenone 5β-reductase , cortisone 5β-reductase , cortisone Δ 4 -5β-reductase , steroid 5β-reductase , testosterone 5β-reductase , Δ 4 -3-ketosteroid 5β-reductase , Δ 4 -5β-reductase , Δ 4 -hydrogenase , 4,5β-dihydrocortisone: NADP + Δ 4 -oxidoreductase , 3-oxo-5β-steroid: NADP + Δ 4 -oxidoreductase ) ni enzyme ifite izina ritunganijwe 5β-cholestan-3-imwe: NADP + 4,5-oxydeductase . Iyi misemburo itera imiti ikurikira (1) 5β-cholestan-3-imwe + NADP + cholest-4-en-3-imwe + NADPH + H + (2) 17,21-dihydroxy-5β-inda-3,11,20-trione + NADP + cortisone + NADPH + H +
5% CE% B2-androstane / Etiocholane: Etiocholane , izwi kandi nka 5β-androstane cyangwa 5-epiandrostane , ni androstane (C19) steroid. Ni 5β-isomer ya androstane. Etiocholanes irimo 5β-androstanedione, 5β-dihydrotestosterone, 3α, 5β-androstanediol, 3β, 5β-androstanediol, etiocholanolone, epietiocholanolone, na 3α, 5β-androstanol.
5% CE% B2-androstane-3,17-dione / Etiocholanedione: Etiocholanedione , izwi kandi nka 5β-androstanedione cyangwa nka etiocholane-3,17-dione , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya andorogene nka testosterone, dihydrotestosterone, dehydroepiandrosterone (DHEA), na Drosta. Ni C5 epimer ya androstanedione (5α-androstanedione). Nubwo idafite ibikorwa bya androgeneque nkibindi 5β byagabanijwe na steroid, etiocholanedione ifite ibikorwa byibinyabuzima byonyine. Urusange rwasanze rufite ingaruka zikomeye za haematopoietic muburyo butandukanye. Byongeye kandi, byagaragaye ko biteza imbere kugabanya ibiro ku nyamaswa ndetse no mu bushakashatsi bw'ubuvuzi bw'impumyi ebyiri, bugenzurwa na platbo mu bantu bwakozwe mu 1993. Izi ngaruka ngo zisa n'iza DHEA. Bitandukanye na DHEA ariko, etiocholanedione ntishobora guhindurwa cyane mumisemburo ya steroid nka andorogene na estrogene.
5% CE% B2-androstane-3% CE% B1,17% CE% B2-diol / 3α-Etiocholanediol: 3α-Etiocholanediol , cyangwa etiocholanediol gusa, izwi kandi nka 3α, 5β-androstanediol cyangwa nka etiocholane-3α, 17β-diol , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya testosterone. Yakozwe kuva 5β-dihydrotestosterone kandi ihinduka na etiocholanolone.
5% CE% B2-androstane-3% CE% B2,17% CE% B2-diol / 3β-Etiocholanediol: 3β-Etiocholanediol , cyangwa epietiocholanediol , izwi kandi nka 3β, 5β-androstanediol cyangwa nka etiocholane-3β, 17β-diol , ni etiocholane (5β-androstane) steroid na metabolite ya endogenous ya testosterone. Yakozwe kuva 5β-dihydrotestosterone kandi ihinduka epietiocholanolone.
5% CE% B2-androstanediol / Etiocholanediol: Etiocholanediol (5β-androstanediol) irashobora kwerekeza kuri: 3α-Etiocholanediol - interogenous intermedia hagati ya epiandrosterone 3β-Etiocholanediol - interogenous intermedia hagati ya epietiocholanolone
5% CE% B2-androstanedione / Etiocholanedione: Etiocholanedione , izwi kandi nka 5β-androstanedione cyangwa nka etiocholane-3,17-dione , ni etiocholane (5β-androstane) steroid na endogenous metabolite ya andorogene nka testosterone, dihydrotestosterone, dehydroepiandrosterone (DHEA), na Drosta. Ni C5 epimer ya androstanedione (5α-androstanedione). Nubwo idafite ibikorwa bya androgeneque nkibindi 5β byagabanijwe na steroid, etiocholanedione ifite ibikorwa byibinyabuzima byonyine. Urusange rwasanze rufite ingaruka zikomeye za haematopoietic muburyo butandukanye. Byongeye kandi, byagaragaye ko biteza imbere kugabanya ibiro ku nyamaswa ndetse no mu bushakashatsi bw'ubuvuzi bw'impumyi ebyiri, bugenzurwa na platbo mu bantu bwakozwe mu 1993. Izi ngaruka ngo zisa n'iza DHEA. Bitandukanye na DHEA ariko, etiocholanedione ntishobora guhindurwa cyane mumisemburo ya steroid nka andorogene na estrogene.
5% CE% B2-androsterone / Etiocholanolone: Etiocholanolone , izwi kandi nka 5β-androsterone , kimwe na 3α-hydroxy-5β-androstan-17-imwe cyangwa etiocholan-3α-ol-17-imwe , ni etiocholane (5β-androstane) steroid kimwe na endogenous 17- ketosteroide ikomoka kuri metabolism ya testosterone. Itera umuriro, immunostimulation, na leukocytose, kandi ikoreshwa mugusuzuma imikorere ya cortex ya adrenal, imikorere yamagufwa, no muburwayi bwa neoplastique kugirango ikangure sisitemu yumubiri. Etiocholanolone izwi kandi ko ari inzitizi ya androstane neurosteroid, ikora nka moderi nziza ya allosteric modulator ya reseptor ya GABA A , kandi ikagira ingaruka za anticonvulsant. Enantiomer idasanzwe ya etiocholanolone irakomeye cyane nka moderi nziza ya allosteric modulator ya GABA A yakira kandi nka anticonvulsant kuruta imiterere karemano.
5% CE% B2-coprostanol / Coprostanol: 5β-Coprostanol ( 5β -cholestan-3β-ol ) ni stanol ya karubone 27 ikomoka kuri biohydrogenation ya cholesterol (cholest-5en-3β-ol) mu nda y'inyamaswa n'inyoni nyinshi. Uru ruganda rwakoreshejwe kenshi nka biomarker kugirango habeho ibintu byangiza abantu mubidukikije.
5% CE% B2-dihydroprogesterone / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-dihydrotestosterone / 5β-Dihydrotestosterone: 5β-Dihydrotestosterone ( 5β-DHT ), izwi kandi nka 5β-androstan-17β-ol-3-imwe cyangwa nka etiocholan-17β-ol-3-imwe , ni etiocholane (5β-androstane) steroid kimwe na metabolite idakora ya testosterone yakozwe na 5β-reductase mu mwijima no mu magufa no hagati mu mikorere ya 3α, 5β-androstanediol na 3β, 5β-androstanediol kandi, muri bo, etiocholanolone na epietiocholanolone. Bitandukanye na isomer yayo 5α-dihydrotestosterone, 5β-DHT ntishobora guhuza cyangwa guhuza intege nke cyane na reseptor ya androgene. 5β-DHT irazwi cyane muri metabolite ya testosterone muri ibyo, kubera guhuza impeta ya A na B mu cyerekezo cya cis , ifite imiterere ya molekulari cyane, kandi ibyo bishobora kuba bifitanye isano no kubura ibikorwa bya andorogene. 5β-DHT, bitandukanye na 5α-DHT, nayo idakora mubijyanye nibikorwa bya neurosteroid, nubwo metabolite yayo, etiocholanolone, ifite ibikorwa nkibi.
5% CE% B2-estran-3% CE% B1-ol-17-umwe / 19-Noretiocholanolone: 19-Noretiocholanolone , izwi kandi nka 5β-estran-3α-ol-17-imwe , ni metabolite ya nandrolone (19-nortestosterone) na bolandione (19-norandrostenedione) ikorwa na 5α-reductase. Ari kurutonde rwibintu bibujijwe n'ikigo cy'isi gishinzwe kurwanya ibiyobyabwenge kuko ari metabolite igaragara ya nandrolone, anabolike-androgeneque steroid (AAS).
5% CE% B2-ethyl-etiocholane / 5β-Gutwita: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-Ethyletiocholane / 5β-Gutwita: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-gutwita-3,20-dione / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-inda / 5β-Inda: 5β-Pregnane , izwi kandi nka 17β-Ethyletiocholane cyangwa nka 10β, 13β-dimethyl-17β-ethyl-5β-gonane , ni steroid hamwe n'ababyeyi bavanga ibintu bitandukanye bikomoka kuri steroid. Nimwe muri epimers yo gutwita, indi ikaba 5α-inda. Ibikomoka kuri 5β-gutwita birimo steroyide isanzwe iboneka 5β-dihydroprogesterone, gutwita, epipregnanolone, gutwita, no gutwita, hamwe na hydroxydione ya sintetike, renanolone, ORG-20599, na SAGE-217. Ibikomokaho birimo metabolite ya progesterone na endogenous na synthèque neurosteroide.
5% CE% B2-inda-3,20-dione / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-inda-3% CE% B1,20% CE% B1-diol 3-glucuronide / glucuronide ya Pregnanediol: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-gutwita-3% CE% B1,20% CE% B1-diol 3% CE% B1-glucuronide / Pregnanediol glucuronide: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-inda-3% CE% B1,20% CE% B1-diol glucuronide / Pregnanediol glucuronide: Pregnanediol glucuronide , cyangwa 5β-gutwita-3α, 20α-diol 3α-glucuronide , ni metabolite ikomeye ya progesterone na conjugate ya C3α glucuronide ya womediediol (5β-inda-3α, 20α-diol). Hafi ya 15 kugeza 30% yumubare wababyeyi wa progesterone uhinduranya muri glucuronide yo gutwita. Mugihe iyi isomer yihariye ivugwa nka glucedion glucuronide kandi ni uburyo bukomeye, mubyukuri hariho isomeri nyinshi zishoboka za metabolite.
5% CE% B2-gutwita / 5β-Dihydroprogesterone: 5β-Dihydroprogesterone ni endogenous neurosteroid kandi Rwisumbuye mu biosynthesis ya pregnanolone na epipregnanolone kuva progesterone. Ihinduranya kuva progesterone na enzyme 5β-reductase.
5% CE% B2-kugabanya / 5β-Kugabanya: 5β-Kugabanya , cyangwa Δ 4 -3-oxosteroid 5β-reductase (EC 1.3.1.3 , 3-oxo-Δ 4 -steroid 5β-reductase , androstenedione 5β-reductase , cholestenone 5β-reductase , cortisone 5β-reductase , cortisone Δ 4 -5β-reductase , steroid 5β-reductase , testosterone 5β-reductase , Δ 4 -3-ketosteroid 5β-reductase , Δ 4 -5β-reductase , Δ 4 -hydrogenase , 4,5β-dihydrocortisone: NADP + Δ 4 -oxidoreductase , 3-oxo-5β-steroid: NADP + Δ 4 -oxidoreductase ) ni enzyme ifite izina ritunganijwe 5β-cholestan-3-imwe: NADP + 4,5-oxydeductase . Iyi misemburo itera imiti ikurikira (1) 5β-cholestan-3-imwe + NADP + cholest-4-en-3-imwe + NADPH + H + (2) 17,21-dihydroxy-5β-inda-3,11,20-trione + NADP + cortisone + NADPH + H +
5% CE% B2-kugabanya / 5β-Kugabanya: 5β-Kugabanya , cyangwa Δ 4 -3-oxosteroid 5β-reductase (EC 1.3.1.3 , 3-oxo-Δ 4 -steroid 5β-reductase , androstenedione 5β-reductase , cholestenone 5β-reductase , cortisone 5β-reductase , cortisone Δ 4 -5β-reductase , steroid 5β-reductase , testosterone 5β-reductase , Δ 4 -3-ketosteroid 5β-reductase , Δ 4 -5β-reductase , Δ 4 -hydrogenase , 4,5β-dihydrocortisone: NADP + Δ 4 -oxidoreductase , 3-oxo-5β-steroid: NADP + Δ 4 -oxidoreductase ) ni enzyme ifite izina ritunganijwe 5β-cholestan-3-imwe: NADP + 4,5-oxydeductase . Iyi misemburo itera imiti ikurikira (1) 5β-cholestan-3-imwe + NADP + cholest-4-en-3-imwe + NADPH + H + (2) 17,21-dihydroxy-5β-inda-3,11,20-trione + NADP + cortisone + NADPH + H +
5% CE% B2-stigmastan-3b-ol / 24-Ethyl coprostanol: 24-Ethyl coprostanol ni 29 ya karubone stanol ikomoka kuri biohydrogenation ya β-sitosterole mu gice cya gastrointestinal yinyamanswa nyinshi cyane cyane ibyatsi. Uru ruganda rwakoreshejwe nka biomarker kugirango habeho ibintu byangiza ubuhinzi (bitari abantu) mubidukikije.
5% E2% 80% 9310% E2% 80% 9315 Amasaha / Amasaha 5-10-15: " Amasaha 5-10-15 " nindirimbo injyana-na-blues yanditswe na Rudy Toombs mu 1952 kuri Ruth Brown kandi yari imwe mu ndirimbo nyinshi za R&B yamwandikiye. Igihe Brown yinjizwaga mu Nzu y'ibyamamare ya Rock na Roll, induction ye yavuze ko "umurimo we mwiza ari ukuboneka ku mpande zitukura zishyushye hagati ya R&B nka 'Amasaha 5-10-15'".
5% E2% 80% 9312 Alexander_Square / Alegizandere Square: Alexander Square ni ubusitani mu karere ka Chelsea mu karere ka Chelsea, SW3. Ubusitani bwa komini hagati yiterambere ni hegitari 0.1226 mubunini.
5% E2% 80% 932 kwirwanaho / 5-2 kwirwanaho: Mu mupira wamaguru wabanyamerika, kwirwanaho 5–2 ni uguhuza kwirwanaho bigizwe nabantu batanu bo hasi hamwe nabakinnyi babiri bakina inyuma.
5% E2% 80% 932% E2% 80% 934 kwirwanaho / 5-2 kwirwanaho: Mu mupira wamaguru wabanyamerika, kwirwanaho 5–2 ni uguhuza kwirwanaho bigizwe nabantu batanu bo hasi hamwe nabakinnyi babiri bakina inyuma.
5% E2% 80% 933 kwirwanaho / 5–3 kwirwanaho: Mu mupira wamaguru wabanyamerika, kwirwanaho 5–3 ni uguhuza kwirwanaho bigizwe nabantu batanu bamanuka hamwe nabakinnyi batatu bakina inyuma.
5% E2% 80% 934% E2% 80% 933% E2% 80% 932% E2% 80% 931 / Mannred Mann: Manfred Mann yari itsinda ry'abongereza ryitwa rock, ryashinzwe i Londres kandi rikomeza kuva mu 1962 kugeza mu 1969. Iri tsinda ryitiriwe izina ryabo ryitwa Manfred Mann, waje kuyobora itsinda ryatsinze itsinda rya Manfred Mann's Earth Band. Iri tsinda ryari rifite abaririmbyi babiri batandukanye, Paul Jones kuva 1962 kugeza 1966, na Mike d'Abo kuva 1966 kugeza 1969.
5% E2% 80% 937 Broad_Street_ (Boston) / 5-7 Umuhanda Mugari (Boston): Umuhanda Mugari 5–7 ni inyubako yamateka i Boston, muri Massachusetts. Igishushanyo mbonera cy'umwubatsi wa Boston, Charles Bulfinch mu 1805, ni imwe mu nyubako nkeya zisigaye z'ubucuruzi mu gihe cy'ubucuruzi hagati y'akarere ka Boston. Yashyizweho ikimenyetso cya Boston mu 1983 na komisiyo ishinzwe ibimenyetso bya Boston kandi iri mu karere ka Custom House House District District.
5% E2% 80% 938 club / 5-8 Club: 5-8 Club Tavern & Grill ni resitora i Minneapolis, Minnesota. Iri funguro ryashinzwe mu 1928 nk'umuvugizi, ni kimwe mu bigo bibiri bya Minneapolis bivuga ko byahimbye cheeseburger ya Juicy Lucy mu myaka ya za 1950, ikindi kikaba Bar's Mat. Club 5-8 ikora kandi burger ya Saucy Sally nibindi biryo birimo ifu ya foromaje ikaranze hamwe nibyatsi byibitunguru. Restaurant yagaragaye kumurongo wa TV Yurugendo rwa TV, ifite ibibanza bitatu byiyongera muri Minnesota.
5% E2% 80% 99UTR / Intara eshanu zingenzi zidasobanuwe: Agace ka 5 ′ kadasobanuwe nakarere ka mRNA iri hejuru yimbere kuva codon yo gutangiza. Aka karere ni ingenzi cyane muguhindura ibisobanuro byinyandiko-mvugo hakoreshejwe uburyo butandukanye muri virusi, prokaryote na eukaryote. Mugihe bitahinduwe, 5 ′ UTR cyangwa igice cyacyo rimwe na rimwe bihindurwa mubicuruzwa bya poroteyine. Ibicuruzwa birashobora noneho kugenzura ibisobanuro byingenzi bikurikirana bya mRNA. Mu binyabuzima byinshi, icyakora, 5 ′ UTR ntabwo ihinduwe rwose, ahubwo ikora urwego rwisumbuye rwa kabiri rwo kugenzura ubusobanuro.
5% E2% 80% 99 iherezo / Icyerekezo (biologiya ya molekuline): Icyerekezo , muri biyolojiya ya biologiya na biohimiya, nicyerekezo cya chimique iherezo-iherezo ryumurongo umwe wa aside nucleique. Mu murongo umwe wa ADN cyangwa RNA, amasezerano yimiti yo kwita atome ya karubone muri nucleotide pentose-isukari-impeta bivuze ko hazaba 5 ′ -end, ikunze kuba irimo itsinda rya fosifate ifatanye na 5 ′ karubone ya ribose impeta, na 3 ′ -end, mubisanzwe idahinduwe kuva ribose -OH. Muri ADN ya kabiri ya helix, imirongo ikora mu cyerekezo gitandukanye kugirango yemererwe guhuza hagati yabo, ari ngombwa mu kwigana cyangwa kwandukura amakuru yashizweho.
5% E2% 80% B2 / Icyerekezo (biologiya ya molekuline): Icyerekezo , muri biyolojiya ya biologiya na biohimiya, nicyerekezo cya chimique iherezo-iherezo ryumurongo umwe wa aside nucleique. Mu murongo umwe wa ADN cyangwa RNA, amasezerano yimiti yo kwita atome ya karubone muri nucleotide pentose-isukari-impeta bivuze ko hazaba 5 ′ -end, ikunze kuba irimo itsinda rya fosifate ifatanye na 5 ′ karubone ya ribose impeta, na 3 ′ -end, mubisanzwe idahinduwe kuva ribose -OH. Muri ADN ya kabiri ya helix, imirongo ikora mu cyerekezo gitandukanye kugirango yemererwe guhuza hagati yabo, ari ngombwa mu kwigana cyangwa kwandukura amakuru yashizweho.
5% E2% 80% B2,5% E2% 80% B3-Dibromo-o-cresolsulfophthalein / Bromocresol yijimye: Bromocresol yijimye ( BCP ) cyangwa 5 ′, 5 ″ -dibromo- o -cresolsulfophthalein , ni irangi ryumuryango wa triphenylmethane hamwe nicyerekana pH. Ifite ibara ry'umuhondo munsi ya pH 5.2, na violet iri hejuru ya pH 6.8. Muburyo bwa cyclic sulfonate ester, ifite p K ifite agaciro ka 6.3, kandi mubisanzwe itegurwa nkigisubizo cyamazi 0,04%.
5% E2% 80% B2,5% E2% 80% B3-dibromo-o-cresolsulfophthalein / Bromocresol yumutuku: Bromocresol yijimye ( BCP ) cyangwa 5 ′, 5 ″ -dibromo- o -cresolsulfophthalein , ni irangi ryumuryango wa triphenylmethane hamwe nicyerekana pH. Ifite ibara ry'umuhondo munsi ya pH 5.2, na violet iri hejuru ya pH 6.8. Muburyo bwa cyclic sulfonate ester, ifite p K ifite agaciro ka 6.3, kandi mubisanzwe itegurwa nkigisubizo cyamazi 0,04%.
5% E2% 80% B2-iherezo / Icyerekezo (ibinyabuzima bya molekuline): Icyerekezo , muri biyolojiya ya biologiya na biohimiya, nicyerekezo cya chimique iherezo-iherezo ryumurongo umwe wa aside nucleique. Mu murongo umwe wa ADN cyangwa RNA, amasezerano yimiti yo kwita atome ya karubone muri nucleotide pentose-isukari-impeta bivuze ko hazaba 5 ′ -end, ikunze kuba irimo itsinda rya fosifate ifatanye na 5 ′ karubone ya ribose impeta, na 3 ′ -end, mubisanzwe idahinduwe kuva ribose -OH. Muri ADN ya kabiri ya helix, imirongo ikora mu cyerekezo gitandukanye kugirango yemererwe guhuza hagati yabo, ari ngombwa mu kwigana cyangwa kwandukura amakuru yashizweho.
5% E2% 80% B2 Cap / Batanu-nyamukuru cap: Muri biologiya ya biologiya, cap-eshanu yibanze ni nucleotide yahinduwe byumwihariko kuri 5 ′ iherezo ryinyandiko-mvugo zimwe na zimwe nka preursor messenger RNA. Iyi nzira, izwi nka capping ya mRNA , iragenzurwa cyane kandi ningirakamaro mugushinga intumwa itajegajega kandi ikuze RNA ibasha guhindurwa mugihe cya synthesis. Mitochondrial mRNA na chloroplastique mRNA ntabwo ifunzwe.
5% E2% 80% B2 UTR / Intara eshanu zingenzi zidasobanuwe: Agace ka 5 ′ kadasobanuwe nakarere ka mRNA iri hejuru yimbere kuva codon yo gutangiza. Aka karere ni ingenzi cyane muguhindura ibisobanuro byinyandiko-mvugo hakoreshejwe uburyo butandukanye muri virusi, prokaryote na eukaryote. Mugihe bitahinduwe, 5 ′ UTR cyangwa igice cyacyo rimwe na rimwe bihindurwa mubicuruzwa bya poroteyine. Ibicuruzwa birashobora noneho kugenzura ibisobanuro byingenzi bikurikirana bya mRNA. Mu binyabuzima byinshi, icyakora, 5 ′ UTR ntabwo ihinduwe rwose, ahubwo ikora urwego rwisumbuye rwa kabiri rwo kugenzura ubusobanuro.
5% E2% 80% B2 cap / Batanu-nyamukuru: Muri biologiya ya biologiya, cap-eshanu yibanze ni nucleotide yahinduwe byumwihariko kuri 5 ′ iherezo ryinyandiko-mvugo zimwe na zimwe nka preursor messenger RNA. Iyi nzira, izwi nka capping ya mRNA , iragenzurwa cyane kandi ningirakamaro mugushinga intumwa itajegajega kandi ikuze RNA ibasha guhindurwa mugihe cya synthesis. Mitochondrial mRNA na chloroplastique mRNA ntabwo ifunzwe.
5% E2% 80% B2 iherezo / Icyerekezo (biologiya ya molekuline): Icyerekezo , muri biyolojiya ya biologiya na biohimiya, nicyerekezo cya chimique iherezo-iherezo ryumurongo umwe wa aside nucleique. Mu murongo umwe wa ADN cyangwa RNA, amasezerano yimiti yo kwita atome ya karubone muri nucleotide pentose-isukari-impeta bivuze ko hazaba 5 ′ -end, ikunze kuba irimo itsinda rya fosifate ifatanye na 5 ′ karubone ya ribose impeta, na 3 ′ -end, mubisanzwe idahinduwe kuva ribose -OH. Muri ADN ya kabiri ya helix, imirongo ikora mu cyerekezo gitandukanye kugirango yemererwe guhuza hagati yabo, ari ngombwa mu kwigana cyangwa kwandukura amakuru yashizweho.
5% E2% 80% B2 kuruhande_karere / 5 region akarere kegeranye: Agace ka 5 ′ kegeranye ni agace ka ADN kegeranye na 5 ′ iherezo rya gene. Agace ka 5 ′ kegeranye karimo porotokoro, kandi irashobora kuba irimo ibyongerera imbaraga cyangwa izindi mbuga za poroteyine zihuza. Nibice bya ADN bitanditswe muri RNA. Ntabwo twakwitiranya nakarere ka 5 ′ kadasobanuwe, kano karere ntabwo kanditswe muri RNA cyangwa ngo gahindurwe muri poroteyine ikora. Utu turere dukora cyane cyane mugutunganya gene transcription. Uturere twegeranye dushyirwa mubice hagati ya prokaryote na eukaryote.
5% E2% 80% B2 idahinduwe_karere / Intara eshanu zingenzi zidasobanuwe: Agace ka 5 ′ kadasobanuwe nakarere ka mRNA iri hejuru yimbere kuva codon yo gutangiza. Aka karere ni ingenzi cyane muguhindura ibisobanuro byinyandiko-mvugo hakoreshejwe uburyo butandukanye muri virusi, prokaryote na eukaryote. Mugihe bitahinduwe, 5 ′ UTR cyangwa igice cyacyo rimwe na rimwe bihindurwa mubicuruzwa bya poroteyine. Ibicuruzwa birashobora noneho kugenzura ibisobanuro byingenzi bikurikirana bya mRNA. Mu binyabuzima byinshi, icyakora, 5 ′ UTR ntabwo ihinduwe rwose, ahubwo ikora urwego rwisumbuye rwa kabiri rwo kugenzura ubusobanuro.
5% E2% 82% 81 ipfundo / Ipfundo rya Cinquefoil: Mu myumvire y'amapfundo , ipfundo rya cinquefoil , rizwi kandi ku izina rya kashe ya Salomo cyangwa ipfundo rya pentafoil , ni rimwe mu mapfundo abiri afite nimero ya gatanu, irindi rikaba ipfundo ry'impande eshatu. Yashyizwe ku ipfundo rya 5 1 mu nyandiko ya Alexander-Briggs, kandi irashobora no gusobanurwa nk ipfundo rya (5,2) -torus. Cinquefoil ni verisiyo ifunze ipfundo ryikubye kabiri.
5% E2% 82% 82 ipfundo / Ipfundo-rigoretse: Mu myumvire y'amapfundo, ipfundo ryibice bitatu ni ipfundo rihindagurika hamwe na kimwe cya gatatu. Yashyizwe ku rutonde rw'amapfundo 5 2 mu nyandiko ya Alexander-Briggs, kandi ni rimwe mu mapfundo abiri yambukiranya nimero ya gatanu, irindi ni ipfundo rya cinquefoil.
5% E2% 82% AC / 5 euro inoti: Inoti eshanu zama euro ( € 5 ) nigiciro gito cyane inoti ya euro kandi yakoreshejwe kuva yatangira kwama euro mumwaka wa 2002. Inoti ikoreshwa mubihugu 25 bifite ifaranga ryonyine; abaturage bagera kuri miliyoni 343. Muri kamena 2020, inoti zigera kuri 1.959.000.000 zama euro azenguruka hafi yama Euro. Ni iya gatanu mu madini akwirakwizwa cyane, angana na 7.8% by'inoti zose. Ikigereranyo cyerekana ko impuzandengo yubunini bwinoti eshanu zama euro zitarenze umwaka mbere yuko isimburwa kubera kwambara.
5% E2% 86% 929% E3% 80% 9C% E7% A7% 81% E3% 81% AB% E6% 81% 8B% E3% 81% 97% E3% 81% 9F% E3% 81% 8A% E5% 9D% 8A% E3% 81% 95% E3% 82% 93% E3% 80% 9C / 5-ji Kara 9-ji Yakozwe: Watashi ni Koi Shita Obōsan: 5-ji Kara 9-ji Yakozwe: Watashi ni Koi Shita Obōsan , ni 2015 ya Fuji TV Yabayapani yerekana ikinamico ikina na Satomi Ishihara na Tomohisa Yamashita. Ikinamico ishingiye kumurongo wa manga Kuva Batanu kugeza Icyenda na Miki Aihara. Yanyuze ku ya 12 Ukwakira 2015 kugeza 14 Ukuboza 2015 hamwe n'ibice 10 byose. Igice cya mbere cyakiriye abareba 12,6% mukarere ka Kantō.
5% E2% 88% 9924 igipimo / 24 Gicurasi ingamba: Ingamba zo ku ya 24 Gicurasi , nazo zitwa 5.24 , ni ibihano Koreya yepfo yafatiye Koreya ya Ruguru ibuza umubano w'ubukungu na Koreya ya Ruguru, yashyizwe mu bikorwa mu rwego rwo kurohama kwa ROKS Cheonan ku ya 26 Werurwe 2010 byaviriyemo abasare 46. Mu Kwakira 2018, guverinoma ya Koreya y'Epfo yatekereje gukuraho ingamba zo kurwanya Koreya y'Amajyaruguru ku ya 24 Gicurasi, nubwo Perezida wa Leta zunze ubumwe za Amerika, Donald Trump yagaragaje ko atishimiye iki cyemezo.
5% EF% B8% 8F% E2% 83% A3 / 5: 5 ( bitanu ) numubare, imibare numubare. Numubare karemano ukurikira 4 na 6 ibanziriza, kandi numubare wambere. Yagize akamaro mu mateka igice kuko abantu basanzwe bafite imibare itanu kuri buri kuboko.
6/6: 6 ( itandatu ) numubare karemano ukurikira 5 nuwabanjirije 7. Numubare uhuriweho numubare muto utunganye.
6% 262 GCR / Itsinda ryanditseho amajwi: Muri siyanse ya mudasobwa, itsinda ryanditseho amajwi cyangwa itsinda ryandika amajwi ( GCR ) bivuga uburyo butandukanye ariko bujyanye na kodegisi ya media. Iya mbere, yakoreshejwe muri 6250 bpi magnetiki kaseti kuva 1973, ni code ikosora amakosa ihujwe nuburebure burebure (RLL) gahunda yo gushushanya, iri mumatsinda ya code ya modulation. Izindi ni disiki nkuru yibanze ya disiki kimwe na disiki ya disiki ya disiki ikoreshwa muri microcomputer zimwe kugeza mu mpera za 1980. GCR nuburyo bwahinduwe bwa kode ya NRZI, ariko byanze bikunze hamwe ninzibacyuho yo hejuru.
6% 262 kodegisi / Itsinda ryanditseho amajwi: Muri siyanse ya mudasobwa, itsinda ryanditseho amajwi cyangwa itsinda ryandika amajwi ( GCR ) bivuga uburyo butandukanye ariko bujyanye na kodegisi ya media. Iya mbere, yakoreshejwe muri 6250 bpi magnetiki kaseti kuva 1973, ni code ikosora amakosa ihujwe nuburebure burebure (RLL) gahunda yo gushushanya, iri mumatsinda ya code ya modulation. Izindi ni disiki nkuru yibanze ya disiki kimwe na disiki ya disiki ya disiki ikoreshwa muri microcomputer zimwe kugeza mu mpera za 1980. GCR nuburyo bwahinduwe bwa kode ya NRZI, ariko byanze bikunze hamwe ninzibacyuho yo hejuru.
6% 27% 27% 27-Hydroxyneomycine C_oxidase / 6 '' '- Hydroxyneomycin C oxydease: 6 '' '- hydroxyneomycin C oxydease (EC 1.1.3.44 , neoG (gene) ) ni enzyme ifite izina ritunganijwe 6' '' - deamino-6 '' '- hydroxyneomycin C: ogisijeni 6' '' - oxydeductase . Iyi misemburo itera imiti ikurikira 6 '' '- deamino-6' '' - hydroxyneomycin C + O 2 6 '' '- deamino-6' '' - oxoneomycine C + H 2 O 2
6% 27% 27% 27-deamino-6% 27% 27% 27-hydroxyneomycine C: ogisijeni_6% 27% 27% 27-oxydeorease / 6 '' '- Hydroxyneomycine C oxydease: 6 '' '- hydroxyneomycin C oxydease (EC 1.1.3.44 , neoG (gene) ) ni enzyme ifite izina ritunganijwe 6' '' - deamino-6 '' '- hydroxyneomycin C: ogisijeni 6' '' - oxydeductase . Iyi misemburo itera imiti ikurikira 6 '' '- deamino-6' '' - hydroxyneomycin C + O 2 6 '' '- deamino-6' '' - oxoneomycine C + H 2 O 2
6% 27,7% 27-Dihydroxybergamottin / 6 ', 7'-Dihydroxybergamottin: 6 ', 7'-Dihydroxybergamottin ni furanocoumarine isanzwe iboneka muri pomelos, imizabibu, hamwe nicunga rya orange, haba mu gishishwa no mu mbuto. Hamwe na chimique ifitanye isano na chimique bergamottin, bemeza ko ari yo nyirabayazana w'imizabibu n'imbuto nyinshi, aho kunywa citrusi irimo kimwe cyangwa byombi byombi bigira ingaruka kuri metabolism yimiti itandukanye ya farumasi.
6% 27,7% 27-dihydroxybergamottin / 6 ', 7'-Dihydroxybergamottin: 6 ', 7'-Dihydroxybergamottin ni furanocoumarine isanzwe iboneka muri pomelos, imizabibu, hamwe nicunga rya orange, haba mu gishishwa no mu mbuto. Hamwe na chimique ifitanye isano na chimique bergamottin, bemeza ko ari yo nyirabayazana w'imizabibu n'imbuto nyinshi, aho kunywa citrusi irimo kimwe cyangwa byombi byombi bigira ingaruka kuri metabolism yimiti itandukanye ya farumasi.
6% 27-synthase ya Deoxychalcone / 6'-Synthase ya Deoxychalcone: Muri enzymologiya, synthase ya 6'-deoxychalcone (EC 2.3.1.170 ) ni enzyme itera reaction yimiti 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H + 4 CoA + isoliquiritigenin + 3 CO 2 + NADP + + H 2 O.
6% 27-Guanidinonaltrindole / 6'-Guanidinonaltrindole: 6'-Guanidinonaltrindole ( 6'-GNTI ) ni κ - δ-opioid reseptor yatoranijwe ligand ikoreshwa mubushakashatsi bwa siyansi.
6% 27-synthase ya deoxychalcone / 6'-synthase ya Deoxychalcone: Muri enzymologiya, synthase ya 6'-deoxychalcone (EC 2.3.1.170 ) ni enzyme itera reaction yimiti 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H + 4 CoA + isoliquiritigenin + 3 CO 2 + NADP + + H 2 O.
6% 271% 22 / Ubuhungiro muri Guyville: Ubuhungiro muri Guyville ni alubumu ya mbere ya studio yakozwe numuririmbyi w'umunyamerika Liz Phair, yasohotse ku ya 22 Kamena 1993 na Matador Records. Yanditswe muri Idful Music Corporation i Chicago hagati ya 1991 na 1993 kandi yakozwe ku bufatanye na Phair na Brad Wood. Iyi alubumu yakiriwe neza cyane mubucuruzi no mubucuruzi. Muri 2020, yashyizwe ku mwanya wa 56 na Rolling Stone muri Album zayo 500 zikomeye kurutonde rwibihe byose. Kugeza muri Nyakanga 2010, alubumu yari imaze kugurisha kopi 491.000.
6% 272 / 6'2 ": 6 ' . Iyi filime yasohotse ku ya 12 Gicurasi 2005, nyuma isohoka mu rurimi rwa Telugu ifite verisiyo yiswe.
6% 272% 22 / 6'2 ": 6 ' . Iyi filime yasohotse ku ya 12 Gicurasi 2005, nyuma isohoka mu rurimi rwa Telugu ifite verisiyo yiswe.
6% 277% 27/6 Ikirenge 7 Ikirenge: " 6 Foot 7 Foot " nindirimbo yumuraperi wumunyamerika Lil Wayne irimo label mugenzi we Cory Gunz. Yakuwe muri alubumu ya cyenda ya Wayne, Tha Carter IV (2011). Yasohotse kumugaragaro kuri iTunes ku ya 16 Ukuboza 2010. Yakozwe na producer wa "A Milli" Bangladesh. Indirimbo ntangarugero "Umunsi-O" ya Harry Belafonte
6% 277% 27% 27/6 Ikirenge 7 Ikirenge: " 6 Foot 7 Foot " nindirimbo yumuraperi wumunyamerika Lil Wayne irimo label mugenzi we Cory Gunz. Yakuwe muri alubumu ya cyenda ya Wayne, Tha Carter IV (2011). Yasohotse kumugaragaro kuri iTunes ku ya 16 Ukuboza 2010. Yakozwe na producer wa "A Milli" Bangladesh. Indirimbo ntangarugero "Umunsi-O" ya Harry Belafonte
6% 27eren / 6'eren: 6'eren numuyoboro wa tereviziyo wo muri Danemarike ukoreshwa na SBS Discovery Media. Yasimbuye SBS Net ku ya 1 Mutarama 2009.
6 * urwego / Inyenyeri esheshatu: Mu ngabo z'Amerika, ipeti ry'inyenyeri esheshatu ni ipeti ryasabwe guhita risumba urwego rw'inyenyeri eshanu, birashoboka ko rwambarwa na Jenerali w'ingabo cyangwa Admiral wa Navy; ariko, iri sano ntiryigeze ryemerwa kumugaragaro nigisirikare cyangwa na Kongere.
6% 2B2 itsinda / Batandatu wongeyeho Amatsinda abiri kuri Afuganisitani: Itsinda rya gatandatu ryongeyeho Amatsinda abiri kuri Afuganisitani risobanura ihuriro ridasanzwe ry'ibihugu bitandatu bihana imbibi na Afuganisitani, wongeyeho Amerika n'Uburusiya, byakoraga kuva mu 1997 kugeza 2001 bayobowe n'Umuryango w'Abibumbye. Ihuriro ryakoze kugira ngo rishakire igisubizo cy'amahoro cyaba kirimo uruhare rw'umuryango w'amajyaruguru ya Afuganisitani. Nyuma yaje gusuzuma ikibazo cya guverinoma ya nyuma y'abatalibani kuri Afuganisitani.
6% 2B4 cycloaddition / 6 + 4 cycloaddition: [6 + 4] Cycloaddition ni ubwoko bwa cycloaddition hagati ya sisitemu ya atome itandatu na sisitemu ya atom enye, biganisha ku mpeta icumi. Kuberako iyi ari gahunda yo hejuru ya cycloaddition, ibibazo bya periselectivite bivuka hiyongereyeho impungenge zisanzwe zijyanye na regio- na stereoselectivite. Sisitemu esheshatu-atom pi yakoreshejwe mubisubizo harimo ibikomoka kuri tropone na tropone, fulvenes, na cycloheptatriene cobalt.
6% 2B5 / 6 + 5 amategeko: Amategeko ya 6 + 5 yari igitekerezo cy'amategeko agenga ishyirahamwe ryemejwe na FIFA mu nama yo muri Gicurasi 2008, nubwo cyari cyaganiriweho kuva mu 1999. Igitekerezo cyarekuwe muri Kamena 2010. Iri tegeko ryasabaga ko - mu ntangiriro ya buri mukino - buri kipe igomba guhitamo byibuze abakinnyi batandatu bemerewe gukinira ikipe yigihugu yigihugu cyikipe.
6% 2B5 itegeko / 6 + 5 itegeko: Amategeko ya 6 + 5 yari igitekerezo cy'amategeko agenga ishyirahamwe ryemejwe na FIFA mu nama yo muri Gicurasi 2008, nubwo cyari cyaganiriweho kuva mu 1999. Igitekerezo cyarekuwe muri Kamena 2010. Iri tegeko ryasabaga ko - mu ntangiriro ya buri mukino - buri kipe igomba guhitamo byibuze abakinnyi batandatu bemerewe gukinira ikipe yigihugu yigihugu cyikipe.
6% 2B5 amategeko_umupira wamaguru / 6 + 5 itegeko: Amategeko ya 6 + 5 yari igitekerezo cy'amategeko agenga ishyirahamwe ryemejwe na FIFA mu nama yo muri Gicurasi 2008, nubwo cyari cyaganiriweho kuva mu 1999. Igitekerezo cyarekuwe muri Kamena 2010. Iri tegeko ryasabaga ko - mu ntangiriro ya buri mukino - buri kipe igomba guhitamo byibuze abakinnyi batandatu bemerewe gukinira ikipe yigihugu yigihugu cyikipe.