5-HT2a receptor/5-HT2A receptor, 5-HT2c receptor_agonist/5-HT2C receptor agonist

5-HT2a yakira / 5-HT2A yakira: 5-HT 2A yakira ni subtype yumutungo wa 5-HT 2 wo mu muryango wa reseptor ya serotonine kandi ni reseptor ya G ya poroteyine (GPCR). 5-HT 2A yakira ni selile yakira. 5-HT ni ngufi kuri 5-hydroxy-tryptamine, ari serotonine. Ubu ni bwo buryo nyamukuru bushimisha reseptor subtype muri GPCRs ya serotonine, nubwo 5-HT 2A ishobora no kugira ingaruka mbi kubice bimwe na bimwe nka cortex igaragara hamwe na cortex ya orbitofrontal cortex. Iyi reseptor yamenyekanye bwa mbere kubera akamaro kayo nkintego yibiyobyabwenge bya serotonergique nka LSD nibihumyo bya psilocybin. Nyuma yaje kugaruka cyane kuko wasangaga nayo ihuza, byibuze igice, ibikorwa byimiti myinshi igabanya ubukana, cyane cyane idasanzwe.
5-HT2c reseptor_agonist / 5-HT2C reseptor agonist: 5-HT 2C reseptor agonist nicyiciro cyibiyobyabwenge bikora 5-HT 2C . Bakoreweho iperereza kugirango bavure ibintu byinshi birimo umubyibuho ukabije, indwara zo mu mutwe, imikorere mibi y'imibonano mpuzabitsina ndetse no kutagira inkari.
5-HT3 / 5-HT3 yakira: Reseptor ya 5-HT 3 ni iya Cys-loop birenze urugero mumiyoboro ya ion ya ligand (LGICs) bityo ikaba itandukanye muburyo n'imikorere nabandi bose bakira 5-HT (5-hydroxytryptamine, cyangwa serotonine) yakira G protein. reseptors. Uyu muyoboro wa ion ni cation-uhitamo kandi uhuza neuronal depolarisation hamwe nibyishimo muri sisitemu yo hagati na periferique.
5-HT3 antagonist / 5-HT3 antagonist: 5-HT 3 antagonistes , izwi ku izina rya " setrons ", ni icyiciro cyibiyobyabwenge bikora nka antagonist reseptor kuri reseptor ya 5-HT 3 , ubwoko bwa reseptor ya serotonine iboneka mumyanya ndangagitsina ya vagus no mubice bimwe na bimwe ubwonko. Hamwe nibidasanzwe bigaragara kuri alosetron na cilansetron, bikoreshwa mukuvura syndrome de munda, abantu bose barwanya 5-HT 3 ni antemetike, ikoreshwa mukurinda no kuvura isesemi no kuruka. Zifite akamaro kanini mukugenzura isesemi no kuruka biterwa na chimiotherapie ya kanseri kandi bifatwa nkibipimo bya zahabu kubwiyi ntego.
5-HT3 barwanya / 5-HT3 barwanya: 5-HT 3 antagonistes , izwi ku izina rya " setrons ", ni icyiciro cyibiyobyabwenge bikora nka antagonist reseptor kuri reseptor ya 5-HT 3 , ubwoko bwa reseptor ya serotonine iboneka mumyanya ndangagitsina ya vagus no mubice bimwe na bimwe ubwonko. Hamwe nibidasanzwe bigaragara kuri alosetron na cilansetron, bikoreshwa mukuvura syndrome de munda, abantu bose barwanya 5-HT 3 ni antemetike, ikoreshwa mukurinda no kuvura isesemi no kuruka. Zifite akamaro kanini mukugenzura isesemi no kuruka biterwa na chimiotherapie ya kanseri kandi bifatwa nkibipimo bya zahabu kubwiyi ntego.
5-HT3 yakira / 5-HT3 yakira: Reseptor ya 5-HT 3 ni iya Cys-loop birenze urugero mumiyoboro ya ion ya ligand (LGICs) bityo ikaba itandukanye muburyo n'imikorere nabandi bose bakira 5-HT (5-hydroxytryptamine, cyangwa serotonine) yakira G protein. reseptors. Uyu muyoboro wa ion ni cation-uhitamo kandi uhuza neuronal depolarisation hamwe nibyishimo muri sisitemu yo hagati na periferique.
5-HT3 reseptor_antagonist / 5-HT3 antagonist: 5-HT 3 antagonistes , izwi ku izina rya " setrons ", ni icyiciro cyibiyobyabwenge bikora nka antagonist reseptor kuri reseptor ya 5-HT 3 , ubwoko bwa reseptor ya serotonine iboneka mumyanya ndangagitsina ya vagus no mubice bimwe na bimwe ubwonko. Hamwe nibidasanzwe bigaragara kuri alosetron na cilansetron, bikoreshwa mukuvura syndrome de munda, abantu bose barwanya 5-HT 3 ni antemetike, ikoreshwa mukurinda no kuvura isesemi no kuruka. Zifite akamaro kanini mukugenzura isesemi no kuruka biterwa na chimiotherapie ya kanseri kandi bifatwa nkibipimo bya zahabu kubwiyi ntego.
5-HT3 reseptor_antagonist: ibiyobyabwenge_ubuvumbuzi_n_iterambere / 5-HT3 antagonist: 5-HT 3 antagonistes , izwi ku izina rya " setrons ", ni icyiciro cyibiyobyabwenge bikora nka antagonist reseptor kuri reseptor ya 5-HT 3 , ubwoko bwa reseptor ya serotonine iboneka mumyanya ndangagitsina ya vagus no mubice bimwe na bimwe ubwonko. Hamwe nibidasanzwe bigaragara kuri alosetron na cilansetron, bikoreshwa mukuvura syndrome de munda, abantu bose barwanya 5-HT 3 ni antemetike, ikoreshwa mukurinda no kuvura isesemi no kuruka. Zifite akamaro kanini mukugenzura isesemi no kuruka biterwa na chimiotherapie ya kanseri kandi bifatwa nkibipimo bya zahabu kubwiyi ntego.
5-HT4 / 5-HT4 yakira: 5-Hydroxytryptamine reseptor 4 ni poroteyine mu bantu igizwe na gene ya HTR4 .
5-HT4L / 5-HT4 yakira: 5-Hydroxytryptamine reseptor 4 ni poroteyine mu bantu igizwe na gene ya HTR4 .
5-HT4L yakira / 5-HT4 yakira: 5-Hydroxytryptamine reseptor 4 ni poroteyine mu bantu igizwe na gene ya HTR4 .
5-HT4 agonist / Serotonin reseptor agonist: Serotonine reseptor agonist ni agonist ya reseptor imwe cyangwa nyinshi. Bakora reseptor ya serotonine muburyo busa na serotonine, neurotransmitter na hormone hamwe na ligand ya endogenous ya reseptor ya serotonine.
5-HT4 yakira / 5-HT4 yakira: 5-Hydroxytryptamine reseptor 4 ni poroteyine mu bantu igizwe na gene ya HTR4 .
5-HT5 / 5-HT5A yakira: 5-Hydroxytryptamine (serotonine) reseptor 5A , izwi kandi nka HTR5A , ni poroteyine mu bantu iba igizwe na gene ya HTR5A . Agoniste hamwe na antagonistes kuri 5-HT yakira, kimwe na serotonine yo gufata inhibitor, kwerekana promnesic (kwibuka-kuzamura) hamwe na / cyangwa kurwanya anti-amnesic mubihe bitandukanye, kandi 5-HT yakira nayo ifitanye isano nimpinduka zubwonko.
5-HT5A / 5-HT5A yakira: 5-Hydroxytryptamine (serotonine) reseptor 5A , izwi kandi nka HTR5A , ni poroteyine mu bantu iba igizwe na gene ya HTR5A . Agoniste hamwe na antagonistes kuri 5-HT yakira, kimwe na serotonine yo gufata inhibitor, kwerekana promnesic (kwibuka-kuzamura) hamwe na / cyangwa kurwanya anti-amnesic mubihe bitandukanye, kandi 5-HT yakira nayo ifitanye isano nimpinduka zubwonko.
5-HT5A yakira / 5-HT5A yakira: 5-Hydroxytryptamine (serotonine) reseptor 5A , izwi kandi nka HTR5A , ni poroteyine mu bantu iba igizwe na gene ya HTR5A . Agoniste hamwe na antagonistes kuri 5-HT yakira, kimwe na serotonine yo gufata inhibitor, kwerekana promnesic (kwibuka-kuzamura) hamwe na / cyangwa kurwanya anti-amnesic mubihe bitandukanye, kandi 5-HT yakira nayo ifitanye isano nimpinduka zubwonko.
5-HT5B yakira / 5-HT5B yakira: 5-HT 5B yakira ni proteine ​​ya 5-HT yakira na gene iyifunga. Poroteyine iboneka mu nzoka, ariko ntiziboneka mu bantu, kubera ko guhagarika code mu buryo bwa code ikurikirana bibuza gene kwerekana poroteyine ikora. Byizerwa ko imikorere ya 5-HT 5B yakira abantu yasimbuwe mubantu nandi matsinda mato ya reseptor ya 5-HT. 5-HT 5B yakira ni G ya proteine ​​ihujwe na reseptor. 5-HT 5B reseptor mRNA igaragarira cyane cyane muri habenula, hippocampus na olive yo hasi yubwonko bwimbeba. Azwi cyane agoniste kuri 5-HT 5B harimo ergotamine na LSD. Abazwi bazwi harimo methiothepin.
5-HT5 yakira / 5-HT5A yakira: 5-Hydroxytryptamine (serotonine) reseptor 5A , izwi kandi nka HTR5A , ni poroteyine mu bantu iba igizwe na gene ya HTR5A . Agoniste hamwe na antagonistes kuri 5-HT yakira, kimwe na serotonine yo gufata inhibitor, kwerekana promnesic (kwibuka-kuzamura) hamwe na / cyangwa kurwanya anti-amnesic mubihe bitandukanye, kandi 5-HT yakira nayo ifitanye isano nimpinduka zubwonko.
5-HT6 / 5-HT6 yakira: 5HT 6 yakira ni subtype ya 5HT reseptor ihuza endogenous neurotransmitter serotonine (5-hydroxytryptamine, 5HT). Ni G proteine ​​ihujwe na reseptor (GPCR) ihujwe na G s kandi igahuza neurotransmission ishimishije. HTR6 yerekana gene yumuntu ikora reseptor.
5-HT6 yakira / 5-HT6 yakira: 5HT 6 yakira ni subtype ya 5HT reseptor ihuza endogenous neurotransmitter serotonine (5-hydroxytryptamine, 5HT). Ni G proteine ​​ihujwe na reseptor (GPCR) ihujwe na G s kandi igahuza neurotransmission ishimishije. HTR6 yerekana gene yumuntu ikora reseptor.
5-HT7 / 5-HT7 yakira: 5-HT 7 yakira ni umunyamuryango wa GPCR birenze urugero byakira selile kandi bigakorwa na neurotransmitter serotonine (5-hydroxytryptamine, 5-HT) reseptor ya 5-HT 7 ihujwe na G s (itera umusaruro kubyara indangururamajwi yerekana molekile cAMP) kandi igaragarira mubice bitandukanye byabantu, cyane cyane mubwonko, inzira ya gastrointestinal, no mumitsi itandukanye. Iyi reseptor yabaye intego yo guteza imbere ibiyobyabwenge kuvura indwara nyinshi zamavuriro. Reseptor ya 5-HT 7 igizwe na gene ya HTR7 , mubantu yandukuwe muburyo 3 butandukanye.
5-HT7 yakira / 5-HT7 yakira: 5-HT 7 yakira ni umunyamuryango wa GPCR birenze urugero byakira selile kandi bigakorwa na neurotransmitter serotonine (5-hydroxytryptamine, 5-HT) reseptor ya 5-HT 7 ihujwe na G s (itera umusaruro kubyara indangururamajwi yerekana molekile cAMP) kandi igaragarira mubice bitandukanye byabantu, cyane cyane mubwonko, inzira ya gastrointestinal, no mumitsi itandukanye. Iyi reseptor yabaye intego yo guteza imbere ibiyobyabwenge kuvura indwara nyinshi zamavuriro. Reseptor ya 5-HT 7 igizwe na gene ya HTR7 , mubantu yandukuwe muburyo 3 butandukanye.
5-HTP / 5-Hydroxytryptophan: 5-Hydroxytryptophan ( 5-HTP ), izwi kandi ku izina rya oxitriptan , ni aside isanzwe ibaho aside amine na prursor ya chimique ndetse no hagati ya metabolike hagati ya biosynthesis ya neurotransmitter serotonine.
5-HTQ / Bufotenidine: Bufotenidine , izwi kandi ku izina rya 5-hydroxy- N , N , N -trimethyltryptammonium ( 5-HTQ ), ni uburozi bujyanye na bufotenin, serotonine, hamwe na tripitamine ziboneka mu burozi bw'amasaro atandukanye. Ikora nka 5-HT 3 yakira reseptor agonist, kandi yakoreshejwe mubushakashatsi bwa siyanse yiga imikorere ya reseptor ya 5-HT 3 , nubwo ikoreshwa ryagarutsweho nuko, nka amine ya kane, idashobora guhita byambuka amaraso-ubwonko-barrière.
5-HTT / Serotonin utwara: Ubwikorezi bwa serotonine buzwi kandi nka sodium-itwara serotonine itwara kandi ikemura umuryango utwara umuryango 6 umunyamuryango wa 4 ni poroteyine mu bantu igizwe na gen SLC6A4 . SERT ni ubwoko bwa poroteyine itwara monoamine itwara serotonine iva muri synaptique igaruka kuri neuron ya presynaptic.
5-HTTLPR / 5-HTTLPR: 5-HTTLPR ni yononekaye gusubiramwo polymorphic karere mu SLC6A4, mu gene ko kode kuko serotonin transporter.Since mu polymorphism kumenyekana hagati 1990, kimaze ndende iperereza, urugero, mu bijanye byarayoborwaga disorders.A 2006 siyansi ingingo yavugaga ko "impapuro zirenga 300 zita ku myitwarire, mu mutwe, mu bya farumasi no mu zindi nyandiko z'ubuvuzi" zasesenguye polymorphism. Mugihe bikunze kuganirwaho nkurugero rwibikorwa bya gene-ibidukikije, aya makimbirane ararwanywa.
5-HT 1D_umuyobozi / 5-HT1D yakira: 5-hydroxytryptamine (serotonine) reseptor 1D , izwi kandi nka HTR1D , ni reseptor ya 5-HT, ariko kandi yerekana gene yabantu iyifata. 5-HT 1D ikora kuri sisitemu yo hagati yo hagati, kandi igira ingaruka kuri lokomisiyo no guhangayika. Itera kandi vasoconstriction y'amaraso mu bwonko.
5-HT 3_abakira / 5-HT3 yakira: Reseptor ya 5-HT 3 ni iya Cys-loop birenze urugero mumiyoboro ya ion ya ligand (LGICs) bityo ikaba itandukanye muburyo n'imikorere nabandi bose bakira 5-HT (5-hydroxytryptamine, cyangwa serotonine) yakira G protein. reseptors. Uyu muyoboro wa ion ni cation-uhitamo kandi uhuza neuronal depolarisation hamwe nibyishimo muri sisitemu yo hagati na periferique.
5-HT N-acetyl_transferase / Aralkylamine N-acetyltransferase: Aralkylamine N -acetyltransferase ( AANAT ), izwi kandi nka arylalkylamine N -acetyltransferase cyangwa serotonine N -acetyltransferase (SNAT), ni enzyme igira uruhare mukubyara injyana ya melatonine kumanywa / nijoro, muguhindura serotonine. Ari mubantu bashizweho na ~ 2.5 kb gene AANAT irimo exons enye, iherereye kuri chromosome 17q25. Gene isobanurwa muri enzyme ya 23 kDa. Yabitswe neza binyuze mu bwihindurize kandi uburyo bwa poroteyine bwa muntu burasa 80 ku ijana n'intama n'imbeba AANAT. Ni enzyme ya acetyl-CoA ishingiye kumuryango wa GCN5 ifitanye isano na N -acetyltransferase (GNATs). Irashobora kugira uruhare mu ndwara zifatika zitandukanye nkimyitwarire ihindagurika mugusinzira / gukanguka kandi ubushakashatsi burakomeza hagamijwe guteza imbere imiti igenga imikorere ya AANAT.
5-HT antagonist / Serotonin reseptor antagonist: Serotonine antagonist , cyangwa serotonine reseptor antagonist , ni imiti ikoreshwa mu guhagarika ibikorwa kuri reseptor ya serotonine (5-HT).
5-HT yakira / 5-HT yakira: 5-HT yakira , 5-hydroxytryptamine yakira , cyangwa reseptor ya serotonine , ni itsinda rya G-protein ihujwe na reseptor ya G hamwe na ioni ya ligand-ion iboneka muri sisitemu yo hagati na peripheri. Bahuza byombi gushimisha no kubuza neurotransmission. Imyakire ya serotonine ikorwa na neurotransmitter serotonine, ikora nka ligand naturel yabo.
5-HT reseptor_2C / 5-HT2C yakira: 5-HT 2C yakira ni subtype ya reseptor ya 5-HT ihuza serotonine ya endogenous neurotransmitter (5-hydroxytryptamine, 5-HT). Ni G proteine ​​ihujwe na reseptor (GPCR) ihujwe na G q / G 11 kandi ihuza neurotransmission ishimishije. HTR2C yerekana gene yumuntu ikora reseptor, ko mubantu iherereye kuri chromosome X. Nkuko igitsina gabo gifite kopi imwe ya gene naho mubigore imwe muri kopi ebyiri za gene irahagarikwa, polymorphism kuri iyi reseptor irashobora kugira ingaruka kubitsina byombi muburyo butandukanye.
5-HT yakira_4 / 5-HT yakira: 5-HT yakira , 5-hydroxytryptamine yakira , cyangwa reseptor ya serotonine , ni itsinda rya G-protein ihujwe na reseptor ya G hamwe na ioni ya ligand-ion iboneka muri sisitemu yo hagati na peripheri. Bahuza byombi gushimisha no kubuza neurotransmission. Imyakire ya serotonine ikorwa na neurotransmitter serotonine, ikora nka ligand naturel yabo.
5-HT yakira / 5-HT yakira: 5-HT yakira , 5-hydroxytryptamine yakira , cyangwa reseptor ya serotonine , ni itsinda rya G-protein ihujwe na reseptor ya G hamwe na ioni ya ligand-ion iboneka muri sisitemu yo hagati na peripheri. Bahuza byombi gushimisha no kubuza neurotransmission. Imyakire ya serotonine ikorwa na neurotransmitter serotonine, ikora nka ligand naturel yabo.
5-HT irekura / Serotonin irekura: Serotonine irekura ( SRA ) ni ubwoko bwibiyobyabwenge bitera kurekura serotonine mumitsi ya synaptic ya neuronal. Serotonine ihitamo kurekura ( SSRA ) ni SRA ifite akamaro gake cyangwa ntigire akamaro mukubyara neurotransmitter efflux kubundi bwoko bwa monoamine neuron.
5-HT kurekura_agent / Serotonine urekura: Serotonine irekura ( SRA ) ni ubwoko bwibiyobyabwenge bitera kurekura serotonine mumitsi ya synaptic ya neuronal. Serotonine ihitamo kurekura ( SSRA ) ni SRA ifite akamaro gake cyangwa ntigire akamaro mukubyara neurotransmitter efflux kubundi bwoko bwa monoamine neuron.
Indwara ya 5-HT / Indwara ya Serotonine: Indwara ya Serotonine ( SS ) ni itsinda ryibimenyetso bishobora kubaho hakoreshejwe imiti imwe n'imwe ya serotonergique. Urwego rwibimenyetso rushobora gutandukana kuva byoroheje bikabije. Ibimenyetso mubihe byoroheje birimo umuvuduko ukabije wamaraso hamwe n umuvuduko wumutima; ubusanzwe nta muriro. Ibimenyetso mubihe bitarimo ubushyuhe bukabije bwumubiri, guhagarika umutima, kwiyongera kwa refleks, guhinda umushyitsi, kubira ibyuya, kwaguka kwabanyeshuri, no gucibwamo. Mubihe bikomeye ubushyuhe bwumubiri burashobora kwiyongera kurenza 41.1 ° C (106.0 ° F). Ingorane zishobora kubamo gufatwa no kugabanuka kwimitsi.
5-HT utwara / Serotonin utwara: Ubwikorezi bwa serotonine buzwi kandi nka sodium-itwara serotonine itwara kandi ikemura umuryango utwara umuryango 6 umunyamuryango wa 4 ni poroteyine mu bantu igizwe na gen SLC6A4 . SERT ni ubwoko bwa poroteyine itwara monoamine itwara serotonine iva muri synaptique igaruka kuri neuron ya presynaptic.
5-Umutwe wa Shark_Igitero / Igitero cya 5-Umutwe: 5-Imitwe ya Shark Attack ni film yo muri 2017 yakozwe na tereviziyo ya sci-fi yerekana amahano yakozwe na The Asylum ifatanije na Syfy. Nubwo hagaragaramo akazu gafite imitwe itanu, iyi filime ni igice cya gatatu mu rukurikirane rwa filime ya Multi-Headed Shark Attack, nyuma y'igitero cy'imitwe 2 ya Shark Attack na 3-imitwe ya Shark Attack ndetse na mbere y'igitero cy'imitwe 6 , hamwe niyi filime irimo bombi a imitwe ine n'imitwe itanu.
5-Histidylcysteine ​​sulfoxide_synthase / 5-Histidylcysteine ​​sulfoxide synthase: 5-Histidylcysteine ​​sulfoxide synthase niyo enzyme yambere muri biosynthesis ya ovothiol, itera okiside yongerera okiside ya sisitemu kuri histidine, ikora 5-histidylcysteine ​​sulfoxide. Enzyme iboneka muri Trypanosomes, aho yongeyeho ifite SAM iterwa na methyl transfert, yongera itsinda rya methyl kuri N1.
Ingufu zamasaha 5 / Ingufu zamasaha 5: Ingufu zamasaha 5 ningufu zakozwe na Amerika "ingufu zirasa" zakozwe na Living Essentials LLC. Isosiyete yashinzwe n'umuyobozi mukuru Manoj Bhargava ikaba yaratangijwe mu 2004.
Ingufu zamasaha 5 (cycling_team) / Ingufu zamasaha 5 (itsinda ryamagare): Ingufu zamasaha 5 nikipe ya UCI Continental cycling club yashinzwe muri 2009 muri Amerika.
Ingufu zamasaha 5_200 / Amasaha 5 yingufu 200: Amasaha 5 Ingufu 200 irashobora kwerekeza kumarushanwa ya NASCAR akurikira: Amasaha 5 yingufu 200, Impeshyi / intangiriro yimpeshyi Igihugu cyose Irushanwa rya Dover International Speedway ryabaye hagati ya 2011 na 2013 Amasaha 5 yingufu 200, Irushanwa ryo Kugwa Igihugu cyose muri Dover International Speedway yabaye guhera 2013
Ingufu zamasaha 5_250 / 5-Amasaha yingufu 250: Ingufu z'amasaha 5-250 yari isiganwa rya NASCAR mu Gihugu hose ryabereye muri World Wide Technology Raceway kuri Gateway i Madison, Illinois.
5-Hydroxy-1,4-naphthoquinone / Juglone: Juglone , nanone yitwa 5-hydroxy-1,4-naphthalenedione (IUPAC) ni ifumbire mvaruganda hamwe na formula ya molekile C 10 H 6 O 3 . Mu nganda zibiribwa, juglone izwi kandi nka CI Natural Brown 7 na CI 75500 . Ntishobora gushonga muri benzene ariko irashobora gushonga muri dioxyde, aho itangirira nk'urushinge rw'umuhondo. Ni isomer ya lawone, arirwo ruganda rwangiza mumababi ya henna.
5-Hydroxy-2 (5H) -furanone / 5-Hydroxy-2 (5H) -furanone: 5-Hydroxy-2 (5 H ) -furanone ni furanone ikomoka kuri okiside ya furfural ikoresheje ogisijeni imwe. Iyi okiside ikorwa muri rusange muri methanol cyangwa Ethanol hamwe na sensibilisateur nka methylene ubururu cyangwa Rose bengal. Uburyo bwiyi reaction bwerekanwe hepfo.
5-Hydroxy-7-mikorerexy-2-methylchromone / Eugenin: Eugenin ni inkomoko ya chromone, ifumbire ya fenolike iboneka mu kantu. Ninimwe mubintu byashinzwe gusharira karoti.
5-Hydroxy-7-mikorerexy-2-methylchrone / Eugenin: Eugenin ni inkomoko ya chromone, ifumbire ya fenolike iboneka mu kantu. Ninimwe mubintu byashinzwe gusharira karoti.
5-Hydroxy-7-imikorerexyflavone / Techtochrysin: Techtochrysin ni imiti ivanze . Ni O-methylated flavone, flavonoide yitandukanije na Prunus cerasus , cheri ikarishye, igihingwa kiva mu Burayi bwinshi no mu majyepfo y'uburengerazuba bwa Aziya.
5-Hydroxy-dimethyltryptamine / Bufotenin: Bufotenin ni inkomoko ya tryptamine ijyanye na neurotransmitter serotonine. Ni alkaloide iboneka mu bwoko bumwebumwe bw'amasaro, ibihumyo n'ibimera byo hejuru.
5-Hydroxy-% CE% B1MT / Alpha-Methylserotonin: α-Methylserotonin ( αMS ), izwi kandi nka α-methyl-5-hydroxytryptamine ( α-methyl-5-HT ) cyangwa 5-hydroxy-α-methyltryptamine ( 5-HO-αMT ), ni inkomoko ya tripitamine ifitanye isano rya hafi na neurotransmitter serotonine (5-HT). Ikora nka serotonine reseptor agonist idatoranya kandi yakoreshejwe cyane mubushakashatsi bwa siyanse kugirango yige imikorere ya sisitemu ya serotonine.
5-HydroxyTryptamine / Serotonine: Serotonine cyangwa 5-hydroxytryptamine ( 5-HT ) ni monoamine neurotransmitter. Imikorere yacyo yibinyabuzima iragoye kandi ifite impande nyinshi, ihindura imyumvire, kumenya, ibihembo, kwiga, kwibuka, hamwe nibikorwa byinshi bya physiologique nko kuruka na vasoconstriction.
5-Hydroxycytosine / 5-Hydroxycytosine: 5-Hydroxycytosine nuburyo bwa okiside ya cytosine ifitanye isano no kwiyongera kwinshuro ya C kugeza kuri T ihinduka, hamwe na C kugeza kuri G. Ntabwo igoreka molekile ya ADN kandi irengerwa byoroshye na polymerase ya ADN yigana.
5-Hydroxyeicosanoid dehydrogenase / 5-Hydroxyeicosanoid dehydrogenase: 5-Hydroxyeicosanoid dehydrogenase ( 5-HEDH ) cyangwa birenze, nicotinamide adenine dinucleotide fosifate (NADP + ) -bishingiye kuri dehydrogenase, ni enzyme ihinduranya umusaruro wa eicosanoide ya arachidonate 5-lipoxygenase (5-LOX), 5 ( S ) -hydroxy -6 S , 8 Z , 11 Z , 14 Z -eicosatetraenoic aside (ni ukuvuga 5- ( S ) -HETE; reba 5-HETE) igereranya na 5-keto, 5-oxo-eicosatetraenoic aside (ni ukuvuga 5-oxo-6 S , 8 Z , 11 Z , 14 Z -eicosatetraenoic aside cyangwa 5-oxo-ETE). Irakora kandi muburyo bwinyuma, metabolizing 5-oxo-ETE kugeza 5 ( S ) -HETE. Kubera ko 5-oxo-ETE ikubye inshuro 30-100 imbaraga zirenze 5 ( S ) -HETE mugukangurira ubwoko butandukanye, 5-HEDH ifatwa nkumuyobozi kandi uteza imbere HETE 5 ( S ) bityo ingaruka za 5-LOX kuri imikorere ya selile. Nubwo 5-HEDH yasuzumwe mu ngirabuzimafatizo zitandukanye kandi mu myiteguro ya microsome idahwitse, ntabwo irasuzumwa ku miterere yayo, kuri gene yayo, mu buryo bwera; ikindi kandi, ubushakashatsi bwinshi kuri bwo bwakorewe mubice byabantu.
5-Hydroxyeicosatetraenoic aside / 5-Acide Hydroxyeicosatetraenoic: 5-Hydroxyeicosatetraenoic aside ni eicosanoide, ni ukuvuga metabolite ya acide arachidonic. Ikorwa nubwoko butandukanye bwimikorere yabantu nandi moko yinyamaswa. Utugingo ngengabuzima dushobora noneho guhinduranya metabolike 5 ( S ) -HETE kugeza 5-oxo-eicosatetraenoic aside (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic aside, cyangwa 5-oxo-15-hydroxyeicosatetraenoic .
5-Hydroxyeicosatetraenoic aside_kandi_5-oxo-eicosatetraenoic_acid / 5-Acide Hydroxyeicosatetraenoic: 5-Hydroxyeicosatetraenoic aside ni eicosanoide, ni ukuvuga metabolite ya acide arachidonic. Ikorwa nubwoko butandukanye bwimikorere yabantu nandi moko yinyamaswa. Utugingo ngengabuzima dushobora noneho guhinduranya metabolike 5 ( S ) -HETE kugeza 5-oxo-eicosatetraenoic aside (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic aside, cyangwa 5-oxo-15-hydroxyeicosatetraenoic .
5-Hydroxyeicosatetraenoic aside_kandi_5-oxo-eicosatetreaenoic_acid / 5-Acide Hydroxyeicosatetraenoic: 5-Hydroxyeicosatetraenoic aside ni eicosanoide, ni ukuvuga metabolite ya acide arachidonic. Ikorwa nubwoko butandukanye bwimikorere yabantu nandi moko yinyamaswa. Utugingo ngengabuzima dushobora noneho guhinduranya metabolike 5 ( S ) -HETE kugeza 5-oxo-eicosatetraenoic aside (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic aside, cyangwa 5-oxo-15-hydroxyeicosatetraenoic .
5-Hydroxyferulic aside / 5-Hydroxyferulic aside: 5-Hydroxyferulic aside ni aside hydroxycinnamic.
5-Hydroxyhydantoin / 5-Hydroxyhydantoin: 5-Hydroxyhydantoin nigicuruzwa cya okiside ya 2′-deoxycytidine. Niba bidakosowe, birashobora gutunganywa na polymerase ya ADN itera inzira ya mutagenic.
5-Hydroxyicosatetraenoic aside / 5-Acide Hydroxyeicosatetraenoic: 5-Hydroxyeicosatetraenoic aside ni eicosanoide, ni ukuvuga metabolite ya acide arachidonic. Ikorwa nubwoko butandukanye bwimikorere yabantu nandi moko yinyamaswa. Utugingo ngengabuzima dushobora noneho guhinduranya metabolike 5 ( S ) -HETE kugeza 5-oxo-eicosatetraenoic aside (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic aside, cyangwa 5-oxo-15-hydroxyeicosatetraenoic .
5-Hydroxyicosatetraenoic aside_kandi_5-oxo-eicosatetraenoic_acid / 5-Acide Hydroxyeicosatetraenoic: 5-Hydroxyeicosatetraenoic aside ni eicosanoide, ni ukuvuga metabolite ya acide arachidonic. Ikorwa nubwoko butandukanye bwimikorere yabantu nandi moko yinyamaswa. Utugingo ngengabuzima dushobora noneho guhinduranya metabolike 5 ( S ) -HETE kugeza 5-oxo-eicosatetraenoic aside (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic aside, cyangwa 5-oxo-15-hydroxyeicosatetraenoic .
5-Hydroxyindole-3-acide acide / 5-Acide Hydroxyindoleacetic: 5-Hydroxyindoleacetic aside (5-HIAA) ni metabolite nyamukuru ya serotonine. Mu gusesengura imiti y'inkari, 5-HIAA ikoreshwa mu kumenya urugero rwa serotonine mu mubiri.
5-Hydroxyindoleacetic aside / 5-Hydroxyindoleacetic aside: 5-Hydroxyindoleacetic aside (5-HIAA) ni metabolite nyamukuru ya serotonine. Mu gusesengura imiti y'inkari, 5-HIAA ikoreshwa mu kumenya urugero rwa serotonine mu mubiri.
5-Hydroxyisourate / 5-Hydroxyisourate: 5-Hydroxyisourate ni molekile ifite formula ya C 5 H 4 N 4 O 4 nuburemere bwa molekile ya 184.110 g / mol. Nibicuruzwa bya okiside ya acide ya uric na urate oxyde.
5-Hydroxymaltol / 5-Hydroxymaltol: 5-Hydroxymaltol , ikomoka kuri maltol, ni ibintu bishobora kuboneka muri Penicillium echinulatum . Iboneka kandi muri oak yuzuye kandi no mubuki buva mumashu yubururu nagasanduku yumuhondo.
5-Hydroxymethyl-2-furaldehyde / Hydroxymethylfurfural: Hydroxymethylfurfural (HMF), nayo 5- (hydroxymethyl) furfural, ni ifumbire mvaruganda iterwa no kubura amazi yisukari. Nibintu byera bishonga cyane bigashonga cyane mumazi no mumashanyarazi. Molekile igizwe nimpeta ya furan, irimo aldehyde hamwe nitsinda ryimikorere ya alcool.
5-Hydroxymethylcytosine / 5-Hydroxymethylcytosine: 5-Hydroxymethylcytosine (5hmC) ni ADN ya pyrimidine ya azote ikomoka kuri cytosine. Birashobora kuba ingenzi muri epigenetique, kubera ko hydroxymethyl groupe kuri cytosine ishobora guhinduranya gene ikazimya. Yagaragaye bwa mbere muri bacteriofage mu 1952. Icyakora, mu 2009 wasangaga ari nyinshi mu bwonko bw'abantu n'imbeba, ndetse no mu ngirabuzimafatizo. Mu nyamaswa z'inyamabere, irashobora kubyara okiside ya 5-methylcytosine, reaction yahujwe na enzymes ya TET. Inzira ya molekile yayo ni C 5 H 7 N 3 O 2 .
5-Hydroxymethylfurfural / Hydroxymethylfurfural: Hydroxymethylfurfural (HMF), nayo 5- (hydroxymethyl) furfural, ni ifumbire mvaruganda iterwa no kubura amazi yisukari. Nibintu byera bishonga cyane bigashonga cyane mumazi no mumashanyarazi. Molekile igizwe nimpeta ya furan, irimo aldehyde hamwe nitsinda ryimikorere ya alcool.
5-Hydroxynaphthoquinone / Juglone: Juglone , nanone yitwa 5-hydroxy-1,4-naphthalenedione (IUPAC) ni ifumbire mvaruganda hamwe na formula ya molekile C 10 H 6 O 3 . Mu nganda zibiribwa, juglone izwi kandi nka CI Natural Brown 7 na CI 75500 . Ntishobora gushonga muri benzene ariko irashobora gushonga muri dioxyde, aho itangirira nk'urushinge rw'umuhondo. Ni isomer ya lawone, arirwo ruganda rwangiza mumababi ya henna.
5-Hydroxytryptamine / Serotonine: Serotonine cyangwa 5-hydroxytryptamine ( 5-HT ) ni monoamine neurotransmitter. Imikorere yacyo yibinyabuzima iragoye kandi ifite impande nyinshi, ihindura imyumvire, kumenya, ibihembo, kwiga, kwibuka, hamwe nibikorwa byinshi bya physiologique nko kuruka na vasoconstriction.
5-Umuyoboro wa Hydroxytryptamine / 5-HT reseptor: 5-HT yakira , 5-hydroxytryptamine yakira , cyangwa reseptor ya serotonine , ni itsinda rya G-protein ihujwe na reseptor ya G hamwe na ioni ya ligand-ion iboneka muri sisitemu yo hagati na peripheri. Bahuza byombi gushimisha no kubuza neurotransmission. Imyakire ya serotonine ikorwa na neurotransmitter serotonine, ikora nka ligand naturel yabo.
5-Hydroxytryptophan / 5-Hydroxytryptophan: 5-Hydroxytryptophan ( 5-HTP ), izwi kandi ku izina rya oxitriptan , ni aside isanzwe ibaho aside amine na prursor ya chimique ndetse no hagati ya metabolike hagati ya biosynthesis ya neurotransmitter serotonine.
5-Hydroxyuracil / 5-Hydroxyuracil: 5-Hydroxyuracil nuburyo bwa okiside ya cytosine ikorwa na okiside yangiza ya cytosine nubwoko bwa ogisijeni ikora. Ntabwo igoreka molekile ya ADN kandi irengerwa na polymerase ya ADN yigana. Irashobora kwibeshya kuri adenine kandi birashoboka ko mutagenic.
5-I / 5I: 5I cyangwa 5-Nshobora kwerekeza kuri: Kode ya IATA ya Air G, nayo yitwa Transair Georgia Amos-5i, icyogajuru cya AsiaSat 2 SSH 5I (WA), reba inzira ya leta ya Washington 510
5-I-R91150 / 5-I-R91150: 5-I-R91150 nuruvange rukora nka antagonist ikomeye kandi itoranya ya 5-HT 2A yakira . Ikoreshwa ryayo nyamukuru nuburyo bwa iyode-123 ya radiolabel, aho ishobora gukoreshwa mugusuzuma SPECT mu bushakashatsi bwakozwe na neuroimaging yabantu, kugirango isuzume ikwirakwizwa ryubwoko bwa 5-HT 2A bwakira mubwonko, urugero kubijyanye n'imibonano mpuzabitsina n'imyaka kandi mubantu bakuru bafite syndrome ya Asperger cyangwa indwara ya Alzheimer.
5-IAI / 5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) ni ikiyobyabwenge gikora nka serotonine, norepinephrine, na dopamine. Yakozwe mu myaka ya za 90 nitsinda riyobowe na David E. Nichols muri kaminuza ya Purdue. 5-IAI isimbuye byimazeyo MDMA mu nzoka kandi ni entactogen ishyira mubantu. Bitandukanye n'ibikomoka kuri aminoindane nka MDAI na MMAI, 5-IAI itera serotonergique neurotoxicity ya imbeba, ariko ikaba idafite uburozi ugereranije na amphetamine homologue ihwanye na pIA, hamwe n'ibyangiritse byagaragaye ko bitageze ku mibare y'imibare.
5-IT / 5-IT: 5- (2-Aminopropyl) indole ni indole na fenethylamine ikomoka hamwe ningaruka zimpuhwe. Imyiteguro yacyo yatangajwe bwa mbere na Albert Hofmann mu 1962. Nibiyobyabwenge byabugenewe byagurishijwe kumugaragaro nkibiyobyabwenge byidagadura nabacuruzi kumurongo kuva 2011.
5-Inch FFAR / 5-Inch Imbere Kurasa Indege Roketi: Indege ya Rocket cyangwa FFAR ya santimetero 5 ni roketi y'Abanyamerika yakozwe mu gihe cy'Intambara ya Kabiri y'Isi Yose kugira ngo ibitero by'indege byibasire ku butaka no ku bwato.
5-Inch Imbere_Firing_Aircraft_Rock / 5-Inch Imbere yo Kurasa Indege Indege: Indege ya Rocket cyangwa FFAR ya santimetero 5 ni roketi y'Abanyamerika yakozwe mu gihe cy'Intambara ya Kabiri y'Isi Yose kugira ngo ibitero by'indege byibasire ku butaka no ku bwato.
5-Indanyl-2-aminopropane / 5-APDI: 5- (2-Aminopropyl) -2,3-dihydro-1 H -indene ( 5-APDI ), izwi kandi nka indanylaminopropane ( IAP ), IAP (psychedelic), 2-API (2-aminopropylindane), indanametamine, na, atari byo, nka indanylamphetamine , ni imiti ya entactogen na psychedelic yumuryango wa amphetamine. Yagurishijwe n'abacuruzi bo kuri interineti binyuze kuri interineti kandi yagiye ihura n'ibiyobyabwenge byabigenewe kuva mu 2003, ariko gukundwa kwayo no kuboneka byagabanutse mu myaka yashize.
5-Iodo-2-aminoindan / 5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) ni ikiyobyabwenge gikora nka serotonine, norepinephrine, na dopamine. Yakozwe mu myaka ya za 90 nitsinda riyobowe na David E. Nichols muri kaminuza ya Purdue. 5-IAI isimbuye byimazeyo MDMA mu nzoka kandi ni entactogen ishyira mubantu. Bitandukanye n'ibikomoka kuri aminoindane nka MDAI na MMAI, 5-IAI itera serotonergique neurotoxicity ya imbeba, ariko ikaba idafite uburozi ugereranije na amphetamine homologue ihwanye na pIA, hamwe n'ibyangiritse byagaragaye ko bitageze ku mibare y'imibare.
5-Iodo-2-aminoindane / 5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) ni ikiyobyabwenge gikora nka serotonine, norepinephrine, na dopamine. Yakozwe mu myaka ya za 90 nitsinda riyobowe na David E. Nichols muri kaminuza ya Purdue. 5-IAI isimbuye byimazeyo MDMA mu nzoka kandi ni entactogen ishyira mubantu. Bitandukanye n'ibikomoka kuri aminoindane nka MDAI na MMAI, 5-IAI itera serotonergique neurotoxicity ya imbeba, ariko ikaba idafite uburozi ugereranije na amphetamine homologue ihwanye na pIA, hamwe n'ibyangiritse byagaragaye ko bitageze ku mibare y'imibare.
5-Iodoaminoindane / 5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) ni ikiyobyabwenge gikora nka serotonine, norepinephrine, na dopamine. Yakozwe mu myaka ya za 90 nitsinda riyobowe na David E. Nichols muri kaminuza ya Purdue. 5-IAI isimbuye byimazeyo MDMA mu nzoka kandi ni entactogen ishyira mubantu. Bitandukanye n'ibikomoka kuri aminoindane nka MDAI na MMAI, 5-IAI itera serotonergique neurotoxicity ya imbeba, ariko ikaba idafite uburozi ugereranije na amphetamine homologue ihwanye na pIA, hamwe n'ibyangiritse byagaragaye ko bitageze ku mibare y'imibare.
5-Iodowillardiine / 5-Iodowillardiine: 5-Iodowillardiine ni agoniste yatoranijwe kuri reseptor ya kainate, ifite ingaruka nke gusa kuri reseptor ya AMPA. Iratoranya kubakira kainate igizwe na GluR5 subunits. Ni neurotoxine ya excitotoxic muri vivo , ariko byagaragaye ko ari ingirakamaro cyane mu kuranga insimburangingo n'imikorere ya reseptor zitandukanye za kainate mu bwonko no mu mugongo.
5-J / 5J: 5J cyangwa 5-J barashobora kwerekeza kuri: Cebu Pacific, indege ya Philippines Moteri ya 5J, ibicuruzwa bya Škoda Fabia Secondary State Highway 5J, izina ryahoze ryumuhanda wa leta ya Washington 702 Destiny of Daleks , Muganga 1979
5-K / 5K: 5K cyangwa 5-K irashobora kwerekeza kuri: 5K ikemurwa, kwerekana ibyerekanwe hamwe na horizontal ikurikirana kurutonde rwa pigiseli 5.000 Gnome-Rhône 5K, moteri yindege ya radiyo Metero 5000, intera ndende yo kwiruka murwego rwo kwiruka 5K kwiruka, amarushanwa maremare yo kwiruka kumuhanda Muraho Fly (indege) Ks eshanu muri Sikhisme, ibintu bitanu Khalsa Sikhs ategekwa kwambara igihe cyose Sander Kleinenberg Yerekana alubumu 5K , 2010 ya DJ Sander Kleinenberg Inzozi za Edeni , Umuganga wo muri 1979
5-Kwiruka kilometero / 5K kwiruka: 5K kwiruka ni amarushanwa maremare yo kwiruka kumuhanda ureshya na kilometero eshanu (3.107 mi). Byitwa kandi isiganwa ryumuhanda 5K , km 5 , cyangwa 5K gusa, ni ngufi cyane mumihanda ikunze kwiruka. Ubusanzwe itandukanijwe na metero 5000 yo kwiruka ibyabaye mukuvuga intera muri kilometero, kuruta metero.
5-L / 5L: 5L cyangwa 5-L irashobora kwerekeza kuri:
5-LO / Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , izwi kandi nka ALOX5 , 5-lipoxygenase , 5-LOX , cyangwa 5-LO , ni enzyme irimo fer idafite ferime mu bantu iba ikozwe na gen ALOX5 . Arachidonate 5-lipoxygenase ni umwe mubagize umuryango wa lipoxygenase ya enzymes. Ihindura amavuta ya acide yingenzi (EFA) substrate muri leukotriène kimwe nibindi bicuruzwa bikoresha ibinyabuzima. ALOX5 ni intego igezweho yo kuvura imiti mu ndwara nyinshi.
5-LOX / Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , izwi kandi nka ALOX5 , 5-lipoxygenase , 5-LOX , cyangwa 5-LO , ni enzyme irimo fer idafite ferime mu bantu iba ikozwe na gen ALOX5 . Arachidonate 5-lipoxygenase ni umwe mubagize umuryango wa lipoxygenase ya enzymes. Ihindura amavuta ya acide yingenzi (EFA) substrate muri leukotriène kimwe nibindi bicuruzwa bikoresha ibinyabuzima. ALOX5 ni intego igezweho yo kuvura imiti mu ndwara nyinshi.
5-LOX inhibitor / Arachidonate 5-lipoxygenase inhibitor: Arachidonate 5-lipoxygenase inhibitor ni ibice bitinda cyangwa bihagarika ibikorwa bya enzyme ya arachidonate 5-lipoxygenase, ishinzwe kubyara leukotriène inflammatory. Umusaruro mwinshi wa leukotriène nimpamvu nyamukuru itera uburibwe muri asima, rhinite ya allergique, na osteoarthritis.
5-LO inhibitor / Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , izwi kandi nka ALOX5 , 5-lipoxygenase , 5-LOX , cyangwa 5-LO , ni enzyme irimo fer idafite ferime mu bantu iba ikozwe na gen ALOX5 . Arachidonate 5-lipoxygenase ni umwe mubagize umuryango wa lipoxygenase ya enzymes. Ihindura amavuta ya acide yingenzi (EFA) substrate muri leukotriène kimwe nibindi bicuruzwa bikoresha ibinyabuzima. ALOX5 ni intego igezweho yo kuvura imiti mu ndwara nyinshi.
5-Umuhanda wa Lexington_Express / 5 (Serivisi ya Metro yo mu mujyi wa New York): 5 Lexington Avenue Express ni serivisi yihuta yo gutambuka muri A Diviziyo ya New York City Metro. Ikirangantego cyacyo, cyangwa "amasasu", gifite ibara rya pome icyatsi kuva ikoresha umurongo wa IRT Lexington Avenue muri Manhattan.
5-Umuhanda wa Lexington_Umuzungu_Ibisobanuro_Umuhanda_Express / 5 (Serivise ya Metro yo mu mujyi wa New York): 5 Lexington Avenue Express ni serivisi yihuta yo gutambuka muri A Diviziyo ya New York City Metro. Ikirangantego cyacyo, cyangwa "amasasu", gifite ibara rya pome icyatsi kuva ikoresha umurongo wa IRT Lexington Avenue muri Manhattan.
5-Lipoxygenase / Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , izwi kandi nka ALOX5 , 5-lipoxygenase , 5-LOX , cyangwa 5-LO , ni enzyme irimo fer idafite ferime mu bantu iba ikozwe na gen ALOX5 . Arachidonate 5-lipoxygenase ni umwe mubagize umuryango wa lipoxygenase ya enzymes. Ihindura amavuta ya acide yingenzi (EFA) substrate muri leukotriène kimwe nibindi bicuruzwa bikoresha ibinyabuzima. ALOX5 ni intego igezweho yo kuvura imiti mu ndwara nyinshi.
5-Lipoxygenase-ikora poroteyine / 5-lipoxygenase ikora poroteyine: Arachidonate 5-lipoxygenase ikora poroteyine izwi kandi nka 5-lipoxygenase ikora poroteyine , cyangwa FLAP , ni poroteyine mu bantu iba irimo geno ya ALOX5AP .
5-Lipoxygenase ikora_protein / 5-poroteyine ikora lipoxygenase: Arachidonate 5-lipoxygenase ikora poroteyine izwi kandi nka 5-lipoxygenase ikora poroteyine , cyangwa FLAP , ni poroteyine mu bantu iba irimo geno ya ALOX5AP .
5-M / 5M: 5M cyangwa 5-M irashobora kwerekeza kuri: Moderi ya 5M, gukemura ibibazo hamwe nuburyo bwo gucunga ibyago bikoreshwa mumutekano windege Sibaviatrans, yahoze ari indege 5M, moteri ya Toyota M. 5M, icyitegererezo cya HP LaserJet 5 Shada , Muganga utarangiye Ninde serial
5-MABB / 5-MBPB: 5-MBPB ni inkomoko ya amphetamine ifitanye isano na MDMA kandi yagurishijwe nk'imiti yabugenewe. Irashobora gusobanurwa nka benzofuran-5-yl analogue ya MBDB cyangwa homologue ya butanamine ya 5-MAPB, kandi ni isomer yubatswe ya 5-EAPB na 6-EAPB. Raporo ya Anecdotal yerekana ko uru ruganda rwagurishijwe nk'imiti ishushanya mu bihugu bitandukanye by'Uburayi kuva mu ntangiriro za 2015, ariko kumenyekanisha bwa mbere kwakozwe mu Kuboza 2015 na laboratoire y'ubucamanza muri Siloveniya.
5-MAPB / 5-MAPB: 5 .
5-MAPDB / 5-MAPDB: 5-MAPDB ( 1- (2,3-dihydrobenzofuran-5-yl) -N-methylpropan-2-amine ) ni imiti ivanga imiti ikora nka entactogenic. Ifitanye isano nuburyo ibiyobyabwenge nka 5-APDB na 5-MAPB, bifite ingaruka zisa na MDMA kandi byakoreshejwe nkibiyobyabwenge. 5-MAPDB yagiye kwiga kumenya z'ibikorwa byayo imiti, kandi basanga kuba ugereranyije gutoranya serotonin releaser, nubwo bikorwa zidakomeye ari releaser ya monoamines n'izindi 5-HT 2 receptor agonist umuryango, bisa myunyu bakuru nka 5- APDB.
5-MAPDI / 5-MAPDI: 5 . Bivugwa ko yagurishijwe ku mbuga za interineti zifite imvi kuva mu 2014, nubwo umwirondoro wa mbere utakozwe neza kugeza muri Nzeri 2016 na laboratoire y'ubucamanza muri Sloveniya.
5-MBPB / 5-MBPB: 5-MBPB ni inkomoko ya amphetamine ifitanye isano na MDMA kandi yagurishijwe nk'imiti yabugenewe. Irashobora gusobanurwa nka benzofuran-5-yl analogue ya MBDB cyangwa homologue ya butanamine ya 5-MAPB, kandi ni isomer yubatswe ya 5-EAPB na 6-EAPB. Raporo ya Anecdotal yerekana ko uru ruganda rwagurishijwe nk'imiti ishushanya mu bihugu bitandukanye by'Uburayi kuva mu ntangiriro za 2015, ariko kumenyekanisha bwa mbere kwakozwe mu Kuboza 2015 na laboratoire y'ubucamanza muri Siloveniya.
5-MEO / 5-MeO-DMT: 5-MeO-DMT ( 5-mikorerexy- N , N -dimethyltryptamine ) ni psychedelic yo mu cyiciro cya tryptamine. Iboneka mubwoko butandukanye bwibimera, kandi byibura ubwoko bumwe bwikibabi, ubutayu bwa Sonoran. Kimwe na bene wabo ba hafi DMT na bufotenin (5-HO-DMT), yakoreshejwe nka entheogen muri Amerika yepfo. Amagambo ya Slang arimo atanu-mikorerexy, Imbaraga, nuburozi bwa Toad.
5-MEO-DMT / 5-MeO-DMT: 5-MeO-DMT ( 5-mikorerexy- N , N -dimethyltryptamine ) ni psychedelic yo mu cyiciro cya tryptamine. Iboneka mubwoko butandukanye bwibimera, kandi byibura ubwoko bumwe bwikibabi, ubutayu bwa Sonoran. Kimwe na bene wabo ba hafi DMT na bufotenin (5-HO-DMT), yakoreshejwe nka entheogen muri Amerika yepfo. Amagambo ya Slang arimo atanu-mikorerexy, Imbaraga, nuburozi bwa Toad.
5-MEO-DiPT / 5-Methoxy-N, N-diisopropyltryptamine: 5-Methoxy- N , N -diisopropyltryptamine ni tryptamine yo mu mutwe hamwe na mikorobe ikomoka kuri diisopropyltryptamine (DiPT).
5-MMPA / 5-Methylmethiopropamine: 5-Methylmethiopropamine ni imiti itera imbaraga ikomoka ku mpeta ikomoka kuri methiopropamine. Ntabwo ikomoka kuri cathinone ikomoka kuri mephedrone, kuko ibuze itsinda rya ketone kuri β umwanya wurunigi rwa alifatique, ahubwo birasa cyane na amphetamine yasimbuwe. Yagurishijwe nkibiyobyabwenge byabugenewe, byamenyekanye bwa mbere mu Budage muri Kamena 2020.
5-MPBP / 5-MBPB: 5-MBPB ni inkomoko ya amphetamine ifitanye isano na MDMA kandi yagurishijwe nk'imiti yabugenewe. Irashobora gusobanurwa nka benzofuran-5-yl analogue ya MBDB cyangwa homologue ya butanamine ya 5-MAPB, kandi ni isomer yubatswe ya 5-EAPB na 6-EAPB. Raporo ya Anecdotal yerekana ko uru ruganda rwagurishijwe nk'imiti ishushanya mu bihugu bitandukanye by'Uburayi kuva mu ntangiriro za 2015, ariko kumenyekanisha bwa mbere kwakozwe mu Kuboza 2015 na laboratoire y'ubucamanza muri Siloveniya.
5-MT / 5-Methoxytryptamine: 5-Methoxytryptamine ( 5-MT ), izwi kandi nka mexamine , ni inkomoko ya tripitamine ifitanye isano rya hafi na neurotransmitters serotonin na melatonin. 5-MT byagaragaye ko bibaho bisanzwe mumubiri murwego rwo hasi. Ni biosynthesize ikoresheje deacetylation ya melatonine muri glande ya pinusi.
5-MTHF / Acide ya Levomefolike: Acide Levomefolic (INN) (izwi kandi nka L-5-MTHF , L -methylfolate na L -5-methyltetrahydrofolate na (6 S ) -5-methyltetrahydrofolate , na (6 S ) -5-MTHF ) nuburyo bwibanze bwibinyabuzima ya folate ikoreshwa kurwego rwa selile kugirango ADN yororoke, cycle ya sisitemu no kugenga homocysteine. Nuburyo buboneka mukuzenguruka no gutwarwa mubice byose mubice no mumaraso - inzitizi yubwonko. Mu ngirabuzimafatizo, L-methylfolate ikoreshwa muri methylation ya homocysteine ​​kugirango ikore methionine na tetrahydrofolate (THF). THF niyakira byihuse igice kimwe cya karubone kugirango ikoreshwe na thymidine-ADN, purine (RNA na ADN) na methionine. Ifishi idafite methylated, aside folike (vitamine B 9 ), nuburyo bwa sintetike ya folate, kandi igomba kugabanywa enzymatique na reductase ya dihydrofolate (DHFR) kugirango ibe ikora mubuzima.
5-Me-MDA / 5-Methyl-MDA: 5-Methyl-3,4-methylenedioxyamphetamine ( 5-Methyl-MDA ) numuti wa entactogen na psychedelic wapanze icyiciro cya amphetamine. Ni impeta-methylated homologue ya MDA hamwe na isomer yubatswe ya MDMA.
5-Me-MIPT / 5, N-Dimethyl-N-isopropyltryptamine: 5, N -Dimethyl- N -isopropyltryptamine ( 5-Me-MiPT ) ni inkomoko ya tryptamine ikekwa ko ari imiti yo mu mutwe. Yakozwe bwa mbere mu 1989. Mu bushakashatsi bwakozwe na vitro kuri homogenates bwerekanye ko bufite reseptor ya serotonine ihuza isano iri hagati ya MiPT na 5-MeO-MiPT, byombi bizwi ko ari imitekerereze ikora mu bantu.
5-Me-MiPT / 5, N-Dimethyl-N-isopropyltryptamine: 5, N -Dimethyl- N -isopropyltryptamine ( 5-Me-MiPT ) ni inkomoko ya tryptamine ikekwa ko ari imiti yo mu mutwe. Yakozwe bwa mbere mu 1989. Mu bushakashatsi bwakozwe na vitro kuri homogenates bwerekanye ko bufite reseptor ya serotonine ihuza isano iri hagati ya MiPT na 5-MeO-MiPT, byombi bizwi ko ari imitekerereze ikora mu bantu.
5-MeO-2, N, N-TMT / 5-MeO-2-TMT: 5-Methoxy-2, N , N -trimethyltryptamine numuti wo mu mutwe wo mu bwoko bwa tryptamine chimique ukora nka psychologique. Byashizwe bwa mbere na Alexander Shulgin kandi bitangazwa mu gitabo cye TiHKAL. 5-MeO-TMT bivugwa ko yerekana ingaruka zo mu mutwe ku kigero cya 75-150 mg mu kanwa, ariko ibyo biroroshye cyane ugereranije n'ibindi bintu bisa. Ibi birerekana ko mugihe itsinda rya methyl kumwanya wa 2 wa molekile ryabujije guhuza imisemburo ya metabolike nka monoamine oxydease (MAO), nayo ibangamira guhuza no / cyangwa gukora serotonine 5-HT 2A reseptor, intego ishinzwe guhuza ingaruka za hallucinogenic zibi bintu.
5-MeO-2-TMT / 5-MeO-2-TMT: 5-Methoxy-2, N , N -trimethyltryptamine numuti wo mu mutwe wo mu bwoko bwa tryptamine chimique ukora nka psychologique. Byashizwe bwa mbere na Alexander Shulgin kandi bitangazwa mu gitabo cye TiHKAL. 5-MeO-TMT bivugwa ko yerekana ingaruka zo mu mutwe ku kigero cya 75-150 mg mu kanwa, ariko ibyo biroroshye cyane ugereranije n'ibindi bintu bisa. Ibi birerekana ko mugihe itsinda rya methyl kumwanya wa 2 wa molekile ryabujije guhuza imisemburo ya metabolike nka monoamine oxydease (MAO), nayo ibangamira guhuza no / cyangwa gukora serotonine 5-HT 2A reseptor, intego ishinzwe guhuza ingaruka za hallucinogenic zibi bintu.
5-MeO-7-TMT / 5-Methoxy-7, N, N-trimethyltryptamine: 5-Methoxy-7, N, N-trimethyltryptamine ( 5-MeO-7, N, N-TMT , 5-MeO-7-TMT ), ni inkomoko ya tryptamine ikora nka agoniste kuri reseptor ya 5-HT 2 serotonine . Mu bizamini by'inyamaswa, byombi 7, N, N-TMT na 5-MeO-7, N, N-TMT byatanze ibisubizo byimyitwarire bisa nibi biyobyabwenge byo mu mutwe nka DMT na 5-MeO-DMT, ariko ibice bifite imyanya 7 nini. insimburangingo nka 7-Ethyl-DMT na 7-bromo-DMT ntabwo yatanze ibisubizo bikwiranye n'imyumvire nubwo yakira 5-HT 2 yakira reseptor ihuza isano, byerekana ko ibyo bishobora kuba arwanya cyangwa intege nke za agoniste kubakira 5-HT 2 . Ihuriro rifitanye isano 7-MeO-MiPT (reba 5-MeO-MiPT) naryo wasangaga ridakora, byerekana ko imyanya 7 idafite kwihanganira nabi amatsinda manini kuriyi myanya, byibuze niba hakenewe ibikorwa bya agoniste.
5-MeO-AET / 5-MeO-AET: 5-Methoxy-alpha-Ethyltryptamine ( 5-MeO-α-ET ) ni imiti yo mu mutwe kandi ni umwe mu bagize imiti ya tryptamine. Itanga imitekerereze, imitekerereze, ningaruka zitera imbaraga.
5-MeO-AI / MEAI: MEAI ni ibiyobyabwenge byidagadura ndetse n'ibiyobyabwenge byo kwirinda kunywa inzoga nyinshi, byasobanuwe bwa mbere mu miti mu 1980, kandi byavuzwe bwa mbere mu miti mu rungano rwasuzumwe mu mwaka wa 2017 na David Nutt n'abandi, bikurikirwa n'undi muri Gashyantare 2018 wasobanuye ibya farumasi, imiti ya farumasi na metabolism ya MEAI . Muri 2018, isosiyete yo muri Amerika yatangiye gutanga ikinyobwa gishingiye kuri MEAI cyitwa "Pace".
5-MeO-AMT / 5-MeO-aMT: 5-MeO-aMT cyangwa 5-mikorerexy-α-methyltryptamine , α, O-Dimethylserotonin ( Alpha-O ) ni tryptamine ikomeye yo mu mutwe. Irashobora gushonga muri Ethanol.
5-MeO-BFE / Dimemebfe: Dimemebfe ( 5-MeO-BFE ) ni imiti yidagadura nubushakashatsi. Ikora nka agonist kumuryango wa 5-HT 1A na 5-HT 2 yumuti wa serotonine. Ifitanye isano nimiterere ikomoka kuri psychedelic tryptamine ikomoka kuri 5-MeO-DMT, ariko hamwe na azote indole isimburwa na ogisijeni, bigatuma dimemebfe ikomoka kuri benzofuran. Irakubye inshuro nyinshi imbaraga nka serotonine agonist kurenza 5-MeO-DMT kandi ifite ibikorwa byinshi kuri 5-HT 1A , ariko iracyerekana ingaruka zikomeye mumuryango wa 5-HT 2 yabakira.
5-MeO-DALT / 5-MeO-DALT: 5-MeO-DALT cyangwa N, N -di allyl-5-mikorerexy tryptamine ni tryptamine ya psychedelic tryptamine yabanje gukomatanya na Alexander Shulgin.